The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere

Stable Identifier
R-HSA-174425
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
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The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere
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The complementary strand is synthesized by the polymerase primase complex using conventional RNA priming.

Literature References
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
telomere maintenance via semi-conservative replication (0032201)
Catalyst Activity
Catalyst Activity
Title
DNA-directed 5'-3' RNA polymerase activity of DNA polymerase alpha:primase:DNA polymerase alpha:G-strand extended telomere end [nucleoplasm]
Physical Entity
DNA polymerase alpha:primase:DNA polymerase alpha:G-strand extended telomere end [nucleoplasm]
Activity
DNA-directed 5'-3' RNA polymerase activity (0003899)
Orthologous Events
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Bos taurus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Caenorhabditis elegans)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Canis familiaris)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Danio rerio)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Dictyostelium discoideum)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Drosophila melanogaster)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Gallus gallus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Mus musculus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Plasmodium falciparum)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Rattus norvegicus)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Saccharomyces cerevisiae)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Schizosaccharomyces pombe)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Sus scrofa)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Xenopus tropicalis)
Authored
Blackburn, EH  (2006-03-10)
Seidel, J  (2006-03-10)
Reviewed
Price, C  (2006-07-13)
Created
Gillespie, ME  (2006-02-17)