Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases

Stable Identifier
R-HSA-170153
Type
Reaction
Species
Homo sapiens
Compartment
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Following its translocation to the nucleus, Cdc25 dephosphorylates and activates nuclear cyclin B1:Cdc2 complexes (Strausfeld et al., 1991).

Literature References
PubMed ID Title Journal Year
1828290 Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

Doree, M, Cavadore, JC, Picard, A, Fesquet, D, Strausfeld, U, Sadhu, K, Russell, P, Labbe, JC

Nature 1991
Participants
Participates
Catalyst Activity

phosphoprotein phosphatase activity of CDC25 [nucleoplasm]

Orthologous Events
Created
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