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MASP2-1(16-444) [extracellular region]
Stable Identifier
R-HSA-166705
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
MASP2 A chain, MASP2-1 isoform 1 A chain
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Conversion of C2 into C2a and C2b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Ficolin-3:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Homo sapiens)
MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Conversion of C4 into C4a and C4b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Ficolin-3:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Homo sapiens)
MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Creation of C4 and C2 activators (Homo sapiens)
Lectin pathway of complement activation (Homo sapiens)
Activation of MASPs (Homo sapiens)
MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Homo sapiens)
Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
Ficolin-3:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Homo sapiens)
MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Homo sapiens)
Activated MASP2-1 [extracellular region] (Homo sapiens)
MASP2-1(16-444) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00187-1 MASP2
Gene Names
MASP2
Participates
as a component of
Activated MASP2-1 [extracellular region] (Homo sapiens)
Other forms of this molecule
MASP2-1 [extracellular region]
MASP2-1(445-686) [extracellular region]
Inferred To
MASP2-1(16-444) [extracellular region]
(Bos taurus)
MASP2-1(16-444) [extracellular region]
(Canis familiaris)
MASP2-1(16-444) [extracellular region]
(Gallus gallus)
MASP2-1(16-444) [extracellular region]
(Mus musculus)
MASP2-1(16-444) [extracellular region]
(Rattus norvegicus)
MASP2-1(16-444) [extracellular region]
(Sus scrofa)
MASP2-1(16-444) [extracellular region]
(Xenopus tropicalis)
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
mannan [ChEBI:28808]
1
alpha-mannan [plasma membrane]
(R-ALL-5621136)
0.75
4
UniProt:P05155 SERPING1
20
SERPING1 [platelet alpha granule lumen]
(R-HSA-139868)
SERPING1 L177P [endoplasmic reticulum lumen]
(R-HSA-9650574)
SERPING1 R400C [endoplasmic reticulum lumen]
(R-HSA-9650511)
SERPING1 V288E [endoplasmic reticulum lumen]
(R-HSA-9650415)
SERPING1 G184_P228del [endoplasmic reticulum lumen]
(R-HSA-9650472)
SERPING1 F236S [endoplasmic reticulum lumen]
(R-HSA-9650538)
SERPING1 T189N [endoplasmic reticulum lumen]
(R-HSA-9650346)
SERPING1 P476L [endoplasmic reticulum lumen]
(R-HSA-9650563)
SERPING1 G184R [endoplasmic reticulum lumen]
(R-HSA-9650424)
SERPING1 P489R [endoplasmic reticulum lumen]
(R-HSA-9650330)
SERPING1 S170P [endoplasmic reticulum lumen]
(R-HSA-9650362)
SERPING1 S280_P282del [endoplasmic reticulum lumen]
(R-HSA-9650522)
SERPING1 V473M [endoplasmic reticulum lumen]
(R-HSA-9650331)
SERPING1 N291H [endoplasmic reticulum lumen]
(R-HSA-9650545)
SERPING1 Q484* [endoplasmic reticulum lumen]
(R-HSA-9650410)
SERPING1 A2_M53del [endoplasmic reticulum lumen]
(R-HSA-9651435)
SERPING1 W482* [endoplasmic reticulum lumen]
(R-HSA-9650502)
SERPING1 Q338* [endoplasmic reticulum lumen]
(R-HSA-9651424)
SERPING1 I196N [endoplasmic reticulum lumen]
(R-HSA-9651390)
SERPING1 S36Ffs*21 [endoplasmic reticulum lumen]
(R-HSA-9651423)
0.676
3
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