uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid

Stable Identifier
R-HSA-162729
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The fatty acid group added to inositol in the fourth step of GPI biosynthsis is removed from GPI-conjugated uPAR. This hydrolysis event occurs in the endoplasmic reticulum and appears to be associated with efficient transport of the conjugated protein from the endoplasmic reticulum to the Golgi apparatus (Tanaka et al. 2004).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
hydrolase activity, acting on ester bonds of PGAP1 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created
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