Reactome | MMP13(77-471) [extracellular region]

MMP13(77-471) [extracellular region]

Stable Identifier

R-HSA-1604755

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

MMP13 intermediate form 77-471, Collagenase 3, MMP13_HUMAN, MMP13

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P45452 MMP13

Gene Names

MMP13

Chain

signal peptide:1-19, propeptide:20-103, chain:104-471

Reference Genes

BioGPS Gene:4322 MMP13

COSMIC (genes):MMP13 MMP13

CTD Gene:4322 MMP13

dbSNP Gene:4322 MMP13

ENSEMBL:ENSG00000137745 MMP13

HGNC:7159 MMP13

KEGG:hsa:4322 MMP13

Monarch:4322 MMP13

NCBI Gene:4322 MMP13

OMIM:600108 MMP13

UCSC:P45452 MMP13

Reference Transcript

RefSeq:NM_002427.3 MMP13

Other Identifiers

11729296_s_at

11729297_at

11752876_x_at

11753168_a_at

11762747_at

16743764

205959_PM_at

205959_at

3388894

3388895

3388896

3388897

3388898

3388899

3388900

3388901

3388902

3388903

3388905

3388906

3388907

3388908

3388910

3388911

3388912

39632_at

4322

7951309

A_23_P138931

A_33_P3221203

GE518683

GO:0001958

GO:0003417

GO:0003824

GO:0004175

GO:0004222

GO:0004252

GO:0005509

GO:0005518

GO:0005576

GO:0005615

GO:0006508

GO:0008233

GO:0008237

GO:0008270

GO:0016787

GO:0022617

GO:0030198

GO:0030282

GO:0030312

GO:0030574

GO:0031012

GO:0046872

GO:0048856

GO:0060349

GO:0140096

GO:1904645

HMNXSV003006395

ILMN_1663873

PH_hs_0000372

TC11002239.hg

X75308_at

g13027796_3p_at

Participates

as a member of

MMP13 intermediate forms [extracellular region] (Homo sapiens)

as an output of

Initial activation of proMMP13 by MMP3 (Homo sapiens)

Other forms of this molecule

MMP13(20-471) [extracellular region]

MMP13(20-76) [extracellular region]

MMP13(55-471) [extracellular region]

MMP13(20-54) [extracellular region]

MMP13(58-471) [extracellular region]

MMP13(20-57) [extracellular region]

MMP13(55-103) [extracellular region]

MMP13(58-103) [extracellular region]

MMP13(77-103) [extracellular region]

MMP13 [extracellular region]

Inferred To

Homologues of MMP13(77-471) [extracellular region] (Caenorhabditis elegans)

Homologues of MMP13(77-471) [extracellular region] (Drosophila melanogaster)

MMP13(77-471) [extracellular region] (Bos taurus)

MMP13(77-471) [extracellular region] (Caenorhabditis elegans)

MMP13(77-471) [extracellular region] (Canis familiaris)

MMP13(77-471) [extracellular region] (Drosophila melanogaster)

MMP13(77-471) [extracellular region] (Gallus gallus)

MMP13(77-471) [extracellular region] (Mus musculus)

MMP13(77-471) [extracellular region] (Rattus norvegicus)

MMP13(77-471) [extracellular region] (Sus scrofa)

MMP13(77-471) [extracellular region] (Xenopus tropicalis)

Cross References

RefSeq

NP_002418.1

ZINC - World Drugs

MMP13_HUMAN

Guide to Pharmacology - Targets

1637

OpenTargets

ENSG00000137745

ENSEMBL

ENST00000260302, ENSP00000260302

ZINC - Substances

MMP13_HUMAN

ZINC - Biogenic

MMP13_HUMAN

ZINC target

P45452

PRO

P45452

GlyGen

P45452

PDB

1PEX, 3O2X, 2E2D, 1XUR, 5B5P, 3WV3, 3I7I, 1EUB, 2PJT, 3TVC, 1XUD, 1XUC, 4JP4, 7JU8, 4FVL, 1YOU, 1ZTQ, 2OZR, 4G0D, 4L19, 3I7G, 4A7B, 3ELM, 5B5O, 5UWL, 5UWK, 2YIG, 3KEJ, 4JPA, 5BOT, 1FLS, 3ZXH, 4FU4, 1FM1, 3KRY, 3LJZ, 2D1N, 2OW9, 5UWN, 5UWM, 3KEK, 3KEC, 5BOY, 3WV1, 5BPA, 830C, 456C, 3WV2

ZINC - Investigational

MMP13_HUMAN

ZINC - Metabolites

MMP13_HUMAN

HPA

ENSG00000137745-MMP13

Pharos - Targets

P45452

Orphanet

MMP13

ZINC - Predictions - Purchasable

MMP13_HUMAN

HMDB Protein

HMDBP02183