Furin cleaves pro-factor X to factor X

Stable Identifier
R-HSA-159733
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
pro-factor X -> factor X + factor X propeptide
Locations in the PathwayBrowser
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Furin, associated with the Golgi membrane, cleaves pro-factor X to form mature, gamma-carboxylated factor X (Wasley et al. 1993).

Literature References
PubMed ID Title Journal Year
8473289 PACE/furin can process the vitamin K-dependent pro-factor IX precursor within the secretory pathway

Wasley, LC, Rehemtulla, A, Bristol, JA, Kaufman, RJ

J. Biol. Chem. 1993
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of FURIN [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Created
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