Expression of TFAM

Stable Identifier
Reaction [omitted]
Homo sapiens
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The TFAM gene is transcribed in the nucleus to yield mRNA and the mRNA is translated to yield precursor protein in the cytosol.

Literature References
PubMed ID Title Journal Year
10412986 Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Spiegelman, BM, Cinti, S, Lowell, B, Wu, Z, Adelmant, G, Mootha, V, Andersson, U, Zhang, C, Scarpulla, RC, Troy, A, Puigserver, P

Cell 1999
8333869 Smaller isoform of human mitochondrial transcription factor 1: its wide distribution and production by alternative splicing

Hayashi, J, Tominaga, K, Ohta, S, Kagawa, Y

Biochem Biophys Res Commun 1993
11340167 Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells

Andersson, U, Scarpulla, RC

Mol Cell Biol 2001
8108407 Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis

Virbasius, JV, Scarpulla, RC

Proc Natl Acad Sci U S A 1994
This event is regulated