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Go!
HRG [extracellular region]
Stable Identifier
R-HSA-158699
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
histidine-rich glycoprotein
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Dissolution of Fibrin Clot (Homo sapiens)
histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Homo sapiens)
HRG [extracellular region] (Homo sapiens)
histidine-rich glycoprotein:plasminogen [extracellular region] (Homo sapiens)
HRG [extracellular region] (Homo sapiens)
histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Homo sapiens)
HRG [extracellular region] (Homo sapiens)
histidine-rich glycoprotein:plasminogen [extracellular region] (Homo sapiens)
HRG [extracellular region] (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Exocytosis of platelet alpha granule contents (Homo sapiens)
Platelet alpha granule contents [extracellular region] (Homo sapiens)
HRG [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04196 HRG
Gene Names
HRG
Chain
signal peptide:1-18, chain:19-525
Reference Genes
BioGPS Gene:3273 HRG
COSMIC (genes):HRG HRG
CTD Gene:3273 HRG
dbSNP Gene:3273 HRG
ENSEMBL:ENSG00000113905 HRG
ENSEMBL_homo_sapiens_GENE:ENSG00000113905.5 HRG
HGNC:5181 HRG
KEGG Gene (Homo sapiens):3273 HRG
Monarch:3273 HRG
NCBI Gene:3273 HRG
OMIM:142640 HRG
UCSC:P04196 HRG
Reference Transcript
RefSeq:NM_000412.4 HRG
Other Identifiers
11756154_a_at
16949334
206226_3p_at
206226_PM_at
206226_at
2656653
2656654
2656655
2656656
2656657
2656658
2656659
2656660
2656661
2656662
2656663
2656664
2656665
2656666
31835_PM_at
31835_at
3273
8084668
A_23_P321892
GE57816
GO:0001525
GO:0002376
GO:0002839
GO:0004867
GO:0004869
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005768
GO:0005773
GO:0005886
GO:0006935
GO:0007010
GO:0007155
GO:0007162
GO:0007596
GO:0007599
GO:0008201
GO:0008270
GO:0008285
GO:0009986
GO:0010468
GO:0010543
GO:0010593
GO:0012501
GO:0015886
GO:0016525
GO:0019865
GO:0020037
GO:0023052
GO:0030168
GO:0030193
GO:0030308
GO:0030312
GO:0031012
GO:0031093
GO:0031410
GO:0032956
GO:0033629
GO:0034330
GO:0036019
GO:0036211
GO:0042060
GO:0042730
GO:0043065
GO:0043226
GO:0043254
GO:0043395
GO:0043537
GO:0046872
GO:0048856
GO:0048870
GO:0050730
GO:0050832
GO:0051838
GO:0051894
GO:0051918
GO:0061844
GO:0062023
GO:0065003
GO:0070062
GO:0072562
GO:0098542
GO:0098772
GO:1900747
GO:2000504
GO:2001027
HMNXSV003044365
ILMN_1807339
ILMN_2193936
M13149_at
PH_hs_0000200
TC03001023.hg
g13518024_3p_at
g13518024_3p_s_at
Participates
as an input of
histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Homo sapiens)
as an output of
histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Homo sapiens)
as a component of
histidine-rich glycoprotein:plasminogen [extracellular region] (Homo sapiens)
as a member of
Platelet alpha granule contents [extracellular region] (Homo sapiens)
Other forms of this molecule
HRG [plasma membrane]
HRG [platelet alpha granule lumen]
Inferred To
Homologues of HRG [extracellular region]
(Xenopus tropicalis)
Hrg [extracellular region]
(Mus musculus)
Hrg [extracellular region]
(Rattus norvegicus)
si:ch211-284e20.8 [extracellular region]
(Danio rerio)
HRG [extracellular region]
(Bos taurus)
HRG [extracellular region]
(Canis familiaris)
HRG [extracellular region]
(Gallus gallus)
HRG [extracellular region]
(Sus scrofa)
MGC69493 [extracellular region]
(Xenopus tropicalis)
hrg [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000403.1
OpenTargets
ENSG00000113905
HPA
ENSG00000113905-HRG
GeneCards
P04196
Ensembl
ENST00000232003
,
ENSP00000232003
,
ENSG00000113905
PRO
P04196
Pharos - Targets
P04196
Orphanet
18923
HMDB Protein
HMDBP02730
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99XU0 Q99XU0
0.602
4
UniProt:O15162 PLS1
0.589
3
UniProt:O76081-6 RGS20
0.556
3
UniProt:A8MQ03 CRTP1
0.556
3
UniProt:Q96PM5 RCHY1
2
RCHY1 [cytosol]
(R-HSA-976013)
RCHY1 [nucleoplasm]
(R-HSA-5655134)
0.543
3
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