Synthesis of PI

Stable Identifier
R-HSA-1483226
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Synthesis of PI
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Phosphatidylinositol (PI) is synthesized when phosphatidic acid (PA) and cytidine triphosphate (CTP) are converted into cytidine diphosphate-diacylglycerol (CDP-DAG) followed by conversion into PI and cytidine monophosphate (CMP) (Stuhne-Sekalec et al 1986, Lykidis et al. 1997).
Literature References
PubMed ID Title Journal Year
9407135 The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content

Rock, CO, Jackson, PD, Jackowski, S, Lykidis, A

J Biol Chem 1997
3718705 Participation of the microsomal CDP-diglycerides in the mitochondrial biosynthesis of phosphatidylglycerol

Stanacev, NZ, Stuhne-Sekalec, L, Chudzik, J

Biochem Cell Biol 1986
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
phosphatidylinositol biosynthetic process (0006661)
Orthologous Events
Synthesis of PI (Bos taurus)
Synthesis of PI (Caenorhabditis elegans)
Synthesis of PI (Canis familiaris)
Synthesis of PI (Danio rerio)
Synthesis of PI (Dictyostelium discoideum)
Synthesis of PI (Drosophila melanogaster)
Synthesis of PI (Gallus gallus)
Synthesis of PI (Mus musculus)
Synthesis of PI (Plasmodium falciparum)
Synthesis of PI (Rattus norvegicus)
Synthesis of PI (Saccharomyces cerevisiae)
Synthesis of PI (Schizosaccharomyces pombe)
Synthesis of PI (Sus scrofa)
Synthesis of PI (Xenopus tropicalis)
Authored
Williams, MG  (2011-09-14)
Reviewed
Wakelam, M  (2012-05-14)
Created
Williams, MG  (2011-08-12)
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