MLCL is acylated to CL by HADH (IM)

Stable Identifier
R-HSA-1482775
Type
Reaction
Species
Homo sapiens
Compartment
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At the inner mitochondrial membrane (IM), the trifunctional enzyme HADH (3-hydroxyacyl-CoA dehydrogenase), an octamer of four alpha (HADHA) and four beta (HADHB) subunits, acylates monolysocardiolipin (MLCL) to cardiolipin (CL) (Taylor & Hatch 2009).

Literature References
PubMed ID Title Journal Year
19737925 Identification of the human mitochondrial linoleoyl-coenzyme A monolysocardiolipin acyltransferase (MLCL AT-1)

Taylor, WA, Hatch, GM

J Biol Chem 2009
Participants
Participates
Catalyst Activity

O-acyltransferase activity of HADH octamer [mitochondrial inner membrane]

Orthologous Events
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