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Sialyl T-antigen (MUC2) [Golgi lumen]
Stable Identifier
R-HSA-1463562
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUC2, MUC2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Homo sapiens)
Sialyl-2,6 T antigens [Golgi lumen] (Homo sapiens)
Sialyl T-antigen (MUC2) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02817 MUC2
Gene Names
MUC2, SMUC
Chain
signal peptide:1-20, chain:21-5289
Reference Genes
BioGPS Gene:4583 MUC2
COSMIC (genes):MUC2 MUC2
CTD Gene:4583 MUC2
dbSNP Gene:4583 MUC2
HGNC:7512 MUC2
KEGG Gene (Homo sapiens):4583 MUC2
Monarch:4583 MUC2
NCBI Gene:4583 MUC2
OMIM:158370 MUC2
Reference Transcript
RefSeq:NM_002457.4 MUC2
Participates
as a member of
Sialyl-2,6 T antigens [Golgi lumen] (Homo sapiens)
Other forms of this molecule
Core 8 (MUC2) [Golgi lumen]
Core 2S (MUC2) [Golgi lumen]
Core 5 (MUC2) [Golgi lumen]
Core 4 (MUC2) [Golgi lumen]
Core 3 (MUC2) [Golgi lumen]
Core 7 (MUC2) [Golgi lumen]
extended Core 6 (MUC2) [Golgi lumen]
GalNAc-MUC2 [plasma membrane]
Core 2 (MUC2) [Golgi lumen]
Core 2a (MUC2) [Golgi lumen]
GalNAc-MUC2 [Golgi lumen]
Sialyl Tn antigen (MUC2) [Golgi lumen]
T-antigen (MUC2) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC2) [Golgi lumen]
Disialyl T-antigen (MUC2) [Golgi lumen]
MUC2 [Golgi lumen]
Core 6 (MUC2) [Golgi lumen]
Inferred To
Hml [Golgi lumen]
(Drosophila melanogaster)
MUC2 [Golgi lumen]
(Bos taurus)
MUC2 [Golgi lumen]
(Canis familiaris)
MUC2 [Golgi lumen]
(Sus scrofa)
Sialyl T-antigen (MUC2) [Golgi lumen]
(Mus musculus)
Sialyl T-antigen (MUC2) [Golgi lumen]
(Rattus norvegicus)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (Gal-beta1,3(Neu5Ac-alpha2,6)GalNAc-alpha group) at unknown position
Modification
Gal-beta1,3(Neu5Ac-alpha2,6)GalNAc-alpha group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_002448.4
OpenTargets
ENSG00000198788
GeneCards
Q02817
PRO
Q02817
Pharos - Targets
Q02817
PDB
7QCU
,
6RBF
,
8CK2
,
8S03
,
6TM6
,
7QCN
,
7A5O
,
7POV
,
7PRL
,
6TM2
,
7PP6
,
7QCL
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