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Sialyl-2,3 T-antigen (MUCL1) [Golgi lumen]
Stable Identifier
R-HSA-1463467
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUCL1, MUCL1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Homo sapiens)
Sialyl-2,3 T antigens [Golgi lumen] (Homo sapiens)
Sialyl-2,3 T-antigen (MUCL1) [Golgi lumen] (Homo sapiens)
ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Homo sapiens)
Sialyl-2,3 T antigens [Golgi lumen] (Homo sapiens)
Sialyl-2,3 T-antigen (MUCL1) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96DR8 MUCL1
Gene Names
MUCL1, SBEM, UNQ590/PRO1160
Chain
signal peptide:1-20, chain:21-90
Reference Genes
BioGPS Gene:118430 MUCL1
COSMIC (genes):MUCL1 MUCL1
CTD Gene:118430 MUCL1
dbSNP Gene:118430 MUCL1
ENSEMBL:ENSG00000172551 MUCL1
ENSEMBL_homo_sapiens_GENE:ENSG00000172551.12 MUCL1
HGNC:30588 MUCL1
KEGG Gene (Homo sapiens):118430 MUCL1
Monarch:118430 MUCL1
NCBI Gene:118430 MUCL1
OMIM:610857 MUCL1
UCSC:Q96DR8 MUCL1
Reference Transcript
RefSeq:NM_058173.2 MUCL1
Other Identifiers
11731021_a_at
118430
1553602_PM_at
1553602_at
16752132
3416704
3416705
3416706
3416708
3416709
3416710
53579_at
7955963
A_14_P115226
A_14_P200640
A_23_P150979
GE515737
GO:0005515
GO:0005576
GO:0005794
GO:0005796
GO:0005886
GO:0016020
GO:0043226
HMNXSV003005127
Hs2.348419.1.S1_3p_at
ILMN_1810978
TC12000471.hg
Participates
as a member of
Sialyl-2,3 T antigens [Golgi lumen] (Homo sapiens)
Other forms of this molecule
Core 8 (MUCL1) [Golgi lumen]
Core 2S (MUCL1) [Golgi lumen]
Core 5 (MUCL1) [Golgi lumen]
Core 4 (MUCL1) [Golgi lumen]
Core 3 (MUCL1) [Golgi lumen]
GalNAc-MUCL1 [plasma membrane]
Core 2 (MUCL1) [Golgi lumen]
Core 2a (MUCL1) [Golgi lumen]
GalNAc-MUCL1 [Golgi lumen]
Sialyl Tn antigen (MUCL1) [Golgi lumen]
T-antigen (MUCL1) [Golgi lumen]
Sialyl T-antigen (MUCL1) [Golgi lumen]
Disialyl T-antigen (MUCL1) [Golgi lumen]
MUCL1 [Golgi lumen]
Core 6 (MUCL1) [Golgi lumen]
extended Core 6 (MUCL1) [Golgi lumen]
Core 7 (MUCL1) [Golgi lumen]
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl group) at unknown position
Modification
alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_477521.1
OpenTargets
ENSG00000172551
HPA
ENSG00000172551-MUCL1
GeneCards
Q96DR8
Ensembl
ENST00000308796
,
ENSG00000172551
,
ENSP00000311364
PRO
Q96DR8
Pharos - Targets
Q96DR8
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q14554 PDIA5
1
PDIA5 [endoplasmic reticulum membrane]
(R-HSA-535514)
0.527
2
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