Reactome | Disialyl T-antigen (MUCL1) [Golgi lumen]

Disialyl T-antigen (MUCL1) [Golgi lumen]

Stable Identifier

R-HSA-1463480

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi lumen

Synonyms

MUCL1, MUCL1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96DR8 MUCL1

Gene Names

MUCL1, SBEM, UNQ590/PRO1160

Chain

signal peptide:1-20, chain:21-90

Reference Genes

BioGPS Gene:118430 MUCL1

COSMIC (genes):MUCL1 MUCL1

CTD Gene:118430 MUCL1

dbSNP Gene:118430 MUCL1

ENSEMBL:ENSG00000172551 MUCL1

HGNC:30588 MUCL1

KEGG Gene (Homo sapiens):118430 MUCL1

Monarch:118430 MUCL1

NCBI Gene:118430 MUCL1

OMIM:610857 MUCL1

UCSC:Q96DR8 MUCL1

Reference Transcript

RefSeq:NM_058173.2 MUCL1

Other Identifiers

11731021_a_at

1553602_PM_at

1553602_at

16752132

3416704

3416705

3416706

3416708

3416709

3416710

53579_at

7955963

A_14_P115226

A_14_P200640

A_23_P150979

GE515737

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005622

GO:0005737

GO:0005794

GO:0005796

GO:0005886

GO:0016020

GO:0043226

HMNXSV003005127

Hs2.348419.1.S1_3p_at

ILMN_1810978

TC12000471.hg

Participates

as a member of

Disialyl T antigens [Golgi lumen] (Homo sapiens)

Other forms of this molecule

Core 8 (MUCL1) [Golgi lumen]

Core 2S (MUCL1) [Golgi lumen]

Core 5 (MUCL1) [Golgi lumen]

Core 4 (MUCL1) [Golgi lumen]

Core 3 (MUCL1) [Golgi lumen]

GalNAc-MUCL1 [plasma membrane]

Core 2 (MUCL1) [Golgi lumen]

Core 2a (MUCL1) [Golgi lumen]

GalNAc-MUCL1 [Golgi lumen]

Sialyl Tn antigen (MUCL1) [Golgi lumen]

T-antigen (MUCL1) [Golgi lumen]

Sialyl-2,3 T-antigen (MUCL1) [Golgi lumen]

Sialyl T-antigen (MUCL1) [Golgi lumen]

MUCL1 [Golgi lumen]

Core 6 (MUCL1) [Golgi lumen]

extended Core 6 (MUCL1) [Golgi lumen]

Core 7 (MUCL1) [Golgi lumen]

Modified Residues

Name

O-(N-acetylamino)galactosyl-L-serine (Neu5Ac-2,6(Neu5Ac-alpha2,3Gal-beta1,3)GalNAc-alpha group) at unknown position

Modification

Neu5Ac-2,6(Neu5Ac-alpha2,3Gal-beta1,3)GalNAc-alpha group

PsiMod Name

O-(N-acetylamino)galactosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.

Cross References

RefSeq

NP_477521.1

OpenTargets

ENSG00000172551

GeneCards

Q96DR8

HPA

ENSG00000172551-MUCL1

Ensembl

ENSG00000172551, ENSP00000311364, ENST00000308796

PRO

Q96DR8

Pharos - Targets

Q96DR8

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3