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pro-defensin alpha 5 is secreted
Stable Identifier
R-HSA-1462005
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
,
secretory granule lumen
ReviewStatus
5/5
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Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Defensins (Homo sapiens)
Alpha-defensins (Homo sapiens)
pro-defensin alpha 5 is secreted (Homo sapiens)
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Pro defensin alpha 5 is secreted from the storage granules of Paneth cells in the small intestine (Porter et al. 1997).
Literature References
PubMed ID
Title
Journal
Year
9169779
Localization of human intestinal defensin 5 in Paneth cell granules
Anton, PA
,
Ganz, T
,
Oren, A
,
Liu, L
,
Porter, EM
Infect Immun
1997
Participants
Input
DEFA5(20-94) [secretory granule lumen]
(Homo sapiens)
Output
DEFA5(20-94) [extracellular region]
(Homo sapiens)
Participates
as an event of
Alpha-defensins (Homo sapiens)
Orthologous Events
pro-defensin alpha 5 is secreted (Mus musculus)
pro-defensin alpha 5 is secreted (Rattus norvegicus)
Authored
Jupe, S (2011-04-28)
Reviewed
McDermott, AM (2011-11-03)
Created
Jupe, S (2011-07-27)
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