Acetylated spermidine (NASPM) is oxidised by the flavoenzyme polyamine oxidase (PAOX, with FAD as cofactor) to produce putrescine (PTCN). PAOX is involved in the back-conversion of polyamines and thus the regulation of their intracellular concentrations (Vujcic et al. 2003).
Diegelman, P, Vujcic, S, Kramer, DL, Porter, CW, Liang, P
N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity of PAOX:FAD [peroxisomal matrix]
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