FASL:FAS Receptor Trimer:FADD complex binds procaspase-10

Stable Identifier
R-HSA-141310
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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FADD recruits caspase-10 precursor (pro-caspase-10) to FASL:FAS receptor trimer (Wang et al. 2001, Sprick et al. 2002).

Literature References
PubMed ID Title Journal Year
12198154 Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8

Sprick, MR, Rieser, E, Stahl, H, Grosse-Wilde, A, Weigand, MA, Walczak, H

EMBO J 2002
11717445 Caspase-10 is an initiator caspase in death receptor signaling

Wang, J, Chun, HJ, Wong, W, Spencer, DM, Lenardo, MJ

Proc Natl Acad Sci U S A 2001
Participants
Participant Of
Orthologous Events
Reviewed
Created