Translocation of BIM to mitochondria

Stable Identifier
R-HSA-139919
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Once BCL2L11 (BIM) dissociates from the cytoskeleton, it translocates to the outer mitochondrial membrane where it associates with BCL2 (Puthalakath et al. 1999).

Literature References
PubMed ID Title Journal Year
10198631 The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

Puthalakath, H, Huang, DC, O'Reilly, LA, King, SM, Strasser, A

Mol Cell 1999
Participants
Participant Of
Event Information
Orthologous Events
Created