Translocation of BMF to mitochondria

Stable Identifier
R-HSA-139909
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, mitochondrial outer membrane
ReviewStatus
5/5
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Translocation of BMF to mitochondria
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Once BMF dissociates from the cytoskeleton, it translocates to the outer mitochondrial membrane where it binds BCL2 (Puthalakath et al. 2001).

Literature References
PubMed ID Title Journal Year
11546872 Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

Beaumont, JG, O'Reilly, LA, Cheney, RE, Coultas, L, Villunger, A, Puthalakath, H, Strasser, A, Huang, DC

Science 2001
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Input
Output
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as an event of
Event Information
Go Biological Process
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway (0001844)
Orthologous Events
Translocation of BMF to mitochondria (Bos taurus)
Translocation of BMF to mitochondria (Canis familiaris)
Translocation of BMF to mitochondria (Danio rerio)
Translocation of BMF to mitochondria (Gallus gallus)
Translocation of BMF to mitochondria (Mus musculus)
Translocation of BMF to mitochondria (Rattus norvegicus)
Translocation of BMF to mitochondria (Sus scrofa)
Translocation of BMF to mitochondria (Xenopus tropicalis)
Created
Hardwick, JM  (2004-08-09)
Tsujimoto, Y  (2004-08-09)
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