Reactome | VEGFC [extracellular region]

VEGFC [extracellular region]

Stable Identifier

R-HSA-139887

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Vascular endothelial growth factor C precursor, Vascular endothelial growth factor related protein, VRP, Flt4 ligand, Flt4- L

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P49767 VEGFC

Gene Names

VEGFC

Chain

signal peptide:1-31, propeptide:32-111, chain:112-227, propeptide:228-419

Reference Genes

BioGPS Gene:7424 VEGFC

COSMIC (genes):VEGFC VEGFC

CTD Gene:7424 VEGFC

dbSNP Gene:7424 VEGFC

ENSEMBL:ENSG00000150630.4 VEGFC

HGNC:12682 VEGFC

KEGG Gene (Homo sapiens):7424 VEGFC

Monarch:7424 VEGFC

NCBI Gene:7424 VEGFC

OMIM:601528 VEGFC

UCSC:P49767 VEGFC

Reference Transcript

RefSeq:NM_005429.4 VEGFC

Other Identifiers

11720163_at

159_at

16981730

1934_s_at

209946_PM_at

209946_at

2794798

2794799

2794800

2794802

2794804

2794811

2794814

2794815

2794816

2794817

2794822

2794823

2794824

2794825

2794826

2794828

7424

8103822

A_23_P167096

GE59158

GO:0001525

GO:0001666

GO:0001934

GO:0001938

GO:0002040

GO:0002052

GO:0002376

GO:0003013

GO:0005172

GO:0005515

GO:0005576

GO:0005615

GO:0006929

GO:0007165

GO:0008083

GO:0008283

GO:0008284

GO:0009410

GO:0009887

GO:0014009

GO:0016020

GO:0016331

GO:0023052

GO:0030154

GO:0030335

GO:0030947

GO:0031093

GO:0031410

GO:0031954

GO:0036211

GO:0038084

GO:0042056

GO:0043185

GO:0043226

GO:0043536

GO:0045668

GO:0045766

GO:0045776

GO:0045860

GO:0048010

GO:0048018

GO:0048856

GO:0048870

GO:0050679

GO:0050714

GO:0050918

GO:0050930

GO:0051781

GO:0060252

GO:0060754

GO:0098772

GO:1901492

GO:1902462

GO:1990830

HMNXSV003056295

ILMN_1701204

PH_hs_0004575

TC04001765.hg

U43142_at

g1373426_3p_at

Participates

as a member of

as a component of

VEGFC dimer [extracellular region] (Homo sapiens)

Other forms of this molecule

VEGFC [platelet alpha granule lumen]

Inferred To

Vegfc [extracellular region] (Mus musculus)

Vegfc [extracellular region] (Rattus norvegicus)

VEGFC [extracellular region] (Bos taurus)

VEGFC [extracellular region] (Canis familiaris)

VEGFC [extracellular region] (Danio rerio)

VEGFC [extracellular region] (Gallus gallus)

VEGFC [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_005420.1

OpenTargets

ENSG00000150630

GeneCards

P49767

HPA

ENSG00000150630-VEGFC

Ensembl

ENSG00000150630, ENSP00000480043, ENST00000618562

PRO

P49767

Pharos - Targets

P49767

Orphanet

22573

PDB

4BSK, 6TJT, 2X1X, 2X1W

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35968 KDR	4	p-11Y-VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) [plasma membrane] (R-HSA-9673636) VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) fusion [plasma membrane] (R-HSA-9673613) VEGFR2 [plasma membrane] (R-HSA-195382) p-6Y-VEGFR2 [plasma membrane] (R-HSA-4420103)	0.693	6