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VEGFC [platelet alpha granule lumen]
Stable Identifier
R-HSA-67159
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
platelet alpha granule lumen
Synonyms
Vascular endothelial growth factor C precursor, Vascular endothelial growth factor related protein, VRP, Flt4 ligand, Flt4- L
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Exocytosis of platelet alpha granule contents (Homo sapiens)
Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)
VEGFs [platelet alpha granule lumen] (Homo sapiens)
VEGFC [platelet alpha granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49767 VEGFC
Gene Names
VEGFC
Chain
signal peptide:1-31, propeptide:32-111, chain:112-227, propeptide:228-419
Reference Genes
BioGPS Gene:7424 VEGFC
COSMIC (genes):VEGFC VEGFC
CTD Gene:7424 VEGFC
dbSNP Gene:7424 VEGFC
ENSEMBL:ENSG00000150630 VEGFC
HGNC:12682 VEGFC
KEGG:hsa:7424 VEGFC
Monarch:7424 VEGFC
NCBI Gene:7424 VEGFC
OMIM:601528 VEGFC
UCSC:P49767 VEGFC
Reference Transcript
RefSeq:NM_005429.4 VEGFC
Other Identifiers
11720163_at
159_at
16981730
1934_s_at
209946_PM_at
209946_at
2794798
2794799
2794800
2794802
2794804
2794805
2794806
2794811
2794814
2794815
2794816
2794817
2794822
2794823
2794824
2794825
2794826
2794828
7424
8103822
A_23_P167096
GE59158
GO:0001525
GO:0001666
GO:0001938
GO:0002040
GO:0002052
GO:0005172
GO:0005515
GO:0005576
GO:0005615
GO:0006929
GO:0007165
GO:0008083
GO:0008283
GO:0008284
GO:0009410
GO:0009887
GO:0014009
GO:0016020
GO:0016331
GO:0030154
GO:0030335
GO:0030947
GO:0031093
GO:0038084
GO:0042056
GO:0043185
GO:0043536
GO:0045668
GO:0045766
GO:0045776
GO:0048010
GO:0048018
GO:0048870
GO:0050679
GO:0050714
GO:0050918
GO:0050930
GO:0051781
GO:0060252
GO:0060754
GO:0098772
GO:1901492
GO:1902462
GO:1990830
HMNXSV003056295
ILMN_1701204
PH_hs_0004575
TC04001765.hg
U43142_at
g1373426_3p_at
Participates
as a member of
VEGFs [platelet alpha granule lumen] (Homo sapiens)
Other forms of this molecule
VEGFC [extracellular region]
Inferred To
VEGFC [platelet alpha granule lumen]
(Bos taurus)
VEGFC [platelet alpha granule lumen]
(Canis familiaris)
VEGFC [platelet alpha granule lumen]
(Gallus gallus)
VEGFC [platelet alpha granule lumen]
(Sus scrofa)
Vegfc [platelet alpha granule lumen]
(Mus musculus)
Vegfc [platelet alpha granule lumen]
(Rattus norvegicus)
vegfc [platelet alpha granule lumen]
(Danio rerio)
Cross References
RefSeq
NP_005420.1
ENSEMBL
ENST00000618562
,
ENSP00000480043
OpenTargets
ENSG00000150630
HPA
ENSG00000150630-VEGFC
PRO
P49767
Pharos - Targets
P49767
GlyGen
P49767
Orphanet
VEGFC
PDB
2X1X
,
2X1W
,
6TJT
,
4BSK
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35968 KDR
5
p-6Y-VEGFR2 [plasma membrane]
(R-HSA-4420103)
VEGFR2 [plasma membrane]
(R-HSA-195382)
p-Y801,Y1054,Y1175-KDR [plasma membrane]
(R-HSA-9860484)
VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) fusion [plasma membrane]
(R-HSA-9673613)
p-11Y-VEGFR2(20-662)insVAGTWTSGLMSL-PDGFRA(471-1089) [plasma membrane]
(R-HSA-9673636)
0.693
6
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