TWIK-releated acid-sensitive K+ channel (TASK)

Stable Identifier
R-HSA-1299316
Type
Pathway
Species
Homo sapiens
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TASK 1 and 3 are closely related both structurally and functionally. TASK1 and TASK3 are activated by extracellular acidification and inhibited by decrease in pH. TASK 1 and Task 3 form functional homodimers and heterodimers, however the biophysical properties of TAS1 and TASK3 heteromers are different form parent subunit properties.

Literature References
PubMed ID Title Journal Year
18824070 Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation

Meuth, SG, Kanyshkov, T, Melzer, N, Bittner, S, Kieseier, BC, Budde, T, Wiendl, H

Neurosci Lett 2008
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