Activation of TASK

Stable Identifier
R-HSA-1299318
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
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Activation of TASK
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TASK are tandem repeat K+ channels that are sensitive to extracellular pH. Activation of TASK results in efflux of K+ into the extracellular space.

Literature References
PubMed ID Title Journal Year
18824070 Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation

Melzer, N, Meuth, SG, Bittner, S, Kanyshkov, T, Wiendl, H, Budde, T, Kieseier, BC

Neurosci Lett 2008
Participants
Input
Output
Participates
as an event of
Catalyst Activity

potassium channel activity of TASK [plasma membrane]

Physical Entity
TASK [plasma membrane] (Homo sapiens)
Activity
potassium channel activity (GO:0005267)
Orthologous Events
Activation of TASK (Bos taurus)
Activation of TASK (Caenorhabditis elegans)
Activation of TASK (Canis familiaris)
Activation of TASK (Danio rerio)
Activation of TASK (Drosophila melanogaster)
Activation of TASK (Gallus gallus)
Activation of TASK (Mus musculus)
Activation of TASK (Rattus norvegicus)
Activation of TASK (Saccharomyces cerevisiae)
Activation of TASK (Sus scrofa)
Activation of TASK (Xenopus tropicalis)
Cross References
Rhea
Authored
Mahajan, SS  (2011-05-22)
Reviewed
Jassal, B  (2010-09-23)
Created
Mahajan, SS  (2011-05-23)
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