Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)

Stable Identifier
R-HSA-1299308
Type
Pathway
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
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Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)
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TWIK channels exhibit very low current and comprise of TWIK1, TWIK2 and KCNK7 members. TWIK current may be low due to rapid recycling of the channels from the plasma membrane.
Literature References
PubMed ID Title Journal Year
19959478 Potassium channel silencing by constitutive endocytosis and intracellular sequestration

Feliciangeli, S, Barhanin, J, Warth, R, Bendahhou, S, Tardy, MP, Chatelain, FC, Sandoz, G, Lesage, F

J Biol Chem 2010
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Orthologous Events
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Bos taurus)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Caenorhabditis elegans)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Canis familiaris)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Danio rerio)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Gallus gallus)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Mus musculus)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Rattus norvegicus)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Saccharomyces cerevisiae)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Sus scrofa)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) (Xenopus tropicalis)
Authored
Mahajan, SS  (2011-05-23)
Reviewed
Jassal, B  (2010-09-23)
Created
Mahajan, SS  (2011-05-23)
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