Activation of tandem pore domain in a weak inwardly rectifying K+ channels

Stable Identifier
R-HSA-1299304
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
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Activation of tandem pore domain in a weak inwardly rectifying K+ channels
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Activation of TWIK channels results in low outward K+ currents.

Literature References
PubMed ID Title Journal Year
19959478 Potassium channel silencing by constitutive endocytosis and intracellular sequestration

Feliciangeli, S, Barhanin, J, Warth, R, Bendahhou, S, Tardy, MP, Chatelain, FC, Sandoz, G, Lesage, F

J Biol Chem 2010
Participants
Input
Output
Participates
as an event of
Catalyst Activity

potassium channel activity of TWIK channels [plasma membrane]

Physical Entity
TWIK channels [plasma membrane] (Homo sapiens)
Activity
potassium channel activity (GO:0005267)
Orthologous Events
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Bos taurus)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Caenorhabditis elegans)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Canis familiaris)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Danio rerio)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Gallus gallus)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Mus musculus)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Rattus norvegicus)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Saccharomyces cerevisiae)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Sus scrofa)
Activation of tandem pore domain in a weak inwardly rectifying K+ channels (Xenopus tropicalis)
Cross References
Rhea
Authored
Mahajan, SS  (2011-05-22)
Reviewed
Jassal, B  (2010-09-23)
Created
Mahajan, SS  (2011-05-23)
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