SAM complex [mitochondrial outer membrane]

Stable Identifier
R-HSA-1252247
Type
Complex
Species
Homo sapiens
Compartment
Synonyms
SAMM50 Complex, TOB Complex
Locations in the PathwayBrowser
General

The SAM complex is inferred from homologous subunits in Saccharomyces cerevisiae. Xie et al. (2007) found human SAM50 in a complex with metaxin 1, metaxin 2, mitofilin, CHCHD3, CHCHD6, and DnaJC1 however Kozjak-Pavlovic et al. (2007) found SAM50 in a separate complex from the metaxins.

Literature References
PubMed ID Title Journal Year
17624330 The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11

Xie, J, Marusich, MF, Souda, P, Whitelegge, J, Capaldi, RA

FEBS Lett 2007
17510655 Conserved roles of Sam50 and metaxins in VDAC biogenesis

Kozjak-Pavlovic, V, Ross, K, Benlasfer, N, Kimmig, S, Karlas, A, Rudel, T

EMBO Rep 2007
Participants
Participant Of
Inferred From