SAM complex [mitochondrial outer membrane]

Stable Identifier
R-HSA-1252247
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Synonyms
SAMM50 Complex, TOB Complex
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General

The SAM complex is inferred from homologous subunits in Saccharomyces cerevisiae. Xie et al. (2007) found human SAM50 in a complex with metaxin 1, metaxin 2, mitofilin, CHCHD3, CHCHD6, and DnaJC1 however Kozjak-Pavlovic et al. (2007) found SAM50 in a separate complex from the metaxins.

Literature References
PubMed ID Title Journal Year
17510655 Conserved roles of Sam50 and metaxins in VDAC biogenesis

Kozjak-Pavlovic, V, Rudel, T, Benlasfer, N, Ross, K, Karlas, A, Kimmig, S

EMBO Rep 2007
17624330 The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11

Xie, J, Capaldi, RA, Whitelegge, J, Marusich, MF, Souda, P

FEBS Lett 2007
Participants
components
Participates
as a component of
as an input of
Inferred From
SAM complex [mitochondrial outer membrane] (Saccharomyces cerevisiae)
Cross References
ComplexPortal
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