CNDP2:2Mn2+ dimer hydrolyses CysGly

Stable Identifier
R-HSA-1247910
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Cytosolic, non-specific peptidase (CNDP2) can hydrolyse cysteinylglycine (CysGly) to release cysteine (L-Cys) and glycine (Gly) (Tuefel et al. 2003). CNDP2 is functional as a homodimer and requires 2 Mn2+ ion per subunit.
Literature References
PubMed ID Title Journal Year
12473676 Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase

Laucher, V, Ledig, JP, Cairns, NJ, Ganzhorn, AJ, Guenet, C, Sauvage, C, Carter, C, Carreau, A, Teufel, M, Smirnova, T, Bernhardt, A, Heintzelmann, B, Boularand, S, Duverger, D, Cowley, DJ, Saudek, V

J Biol Chem 2003
Participants
Participates
Catalyst Activity

carboxypeptidase activity of CNDP2:2Mn2+ dimer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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