CNDP2:2Mn2+ dimer hydrolyses CysGly

Stable Identifier
R-HSA-1247910
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytosolic, non-specific peptidase (CNDP2) can hydrolyse cysteinylglycine (CysGly) to release cysteine (L-Cys) and glycine (Gly) (Tuefel et al. 2003). CNDP2 is functional as a homodimer and requires 2 Mn2+ ion per subunit.

Literature References
PubMed ID Title Journal Year
12473676 Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase

Teufel, M, Saudek, V, Ledig, JP, Bernhardt, A, Boularand, S, Carreau, A, Cairns, NJ, Carter, C, Cowley, DJ, Duverger, D, Ganzhorn, AJ, Guenet, C, Heintzelmann, B, Laucher, V, Sauvage, C, Smirnova, T

J Biol Chem 2003
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
carboxypeptidase activity of CNDP2:2Mn2+ dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created