Reactome | CNDP2:2Mn2+ dimer hydrolyses CysGly

CNDP2:2Mn2+ dimer hydrolyses CysGly

Stable Identifier

R-HSA-1247910

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Cytosolic, non-specific peptidase (CNDP2) can hydrolyse cysteinylglycine (CysGly) to release cysteine (L-Cys) and glycine (Gly) (Tuefel et al. 2003). CNDP2 is functional as a homodimer and requires 2 Mn2+ ion per subunit.

Literature References

PubMed ID	Title	Journal	Year
12473676	Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase Laucher, V, Ledig, JP, Cairns, NJ, Ganzhorn, AJ, Guenet, C, Sauvage, C, Carter, C, Carreau, A, Teufel, M, Smirnova, T, Bernhardt, A, Heintzelmann, B, Boularand, S, Duverger, D, Cowley, DJ, Saudek, V	J Biol Chem	2003