Reactome | CNDP2:2Mn2+ dimer hydrolyses CysGly

CNDP2:2Mn2+ dimer hydrolyses CysGly

Stable Identifier

R-HSA-1247910

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic, non-specific peptidase (CNDP2) can hydrolyse cysteinylglycine (CysGly) to release cysteine (L-Cys) and glycine (Gly) (Tuefel et al. 2003). CNDP2 is functional as a homodimer and requires 2 Mn2+ ion per subunit.

Literature References

PubMed ID	Title	Journal	Year
12473676	Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase Teufel, M, Saudek, V, Ledig, JP, Bernhardt, A, Boularand, S, Carreau, A, Cairns, NJ, Carter, C, Cowley, DJ, Duverger, D, Ganzhorn, AJ, Guenet, C, Heintzelmann, B, Laucher, V, Sauvage, C, Smirnova, T	J Biol Chem	2003