Reactome | H2O2 gets scavenged by unsaturated lipid

H2O2 gets scavenged by unsaturated lipid

Stable Identifier

R-HSA-1222341

Type

Reaction [transition]

Species

Homo sapiens

Related Species

Mycobacterium tuberculosis

Compartment

cytosol

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H2O2 gets scavenged by unsaturated lipid

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Due to their abundance in Mycobacteria, lipids fulfill a buffering role in the tolerance of antioxidants. Lipid production is triggered by oxidative stress. The peroxidated lipid can be reduced by AhpC (Chauhan & Mande 2001).

Literature References

PubMed ID	Title	Journal	Year
11171096	Characterization of the Mycobacterium tuberculosis H37Rv alkyl hydroperoxidase AhpC points to the importance of ionic interactions in oligomerization and activity Chauhan, R, Mande, SC	Biochem J	2001

Participants

Input

Output

Lipid-OOH [cytosol]

Participant Of

hasEvent

Tolerance of reactive oxygen produced by macrophages

Disease

Name	Identifier	Synonyms
tuberculosis	399	tuberculous abscess, Tuberculoma (finding), tuberculoma

Authored

Stephan, R (2011-01-10)

Reviewed

Warner, D (2012-04-30)

Created

Jassal, B (2011-02-28)