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ASH1L [nucleoplasm]
Stable Identifier
R-HSA-1183218
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Probable histone-lysine N-methyltransferase ASH1L, ASH1L_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
PKMTs methylate histone lysines (Homo sapiens)
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Homo sapiens)
WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Homo sapiens)
ASH1L [nucleoplasm] (Homo sapiens)
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Homo sapiens)
WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Homo sapiens)
ASH1L [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NR48 ASH1L
Gene Names
ASH1L, KIAA1420, KMT2H
Chain
chain:1-2969
Reference Genes
BioGPS Gene:55870 ASH1L
COSMIC (genes):ASH1L ASH1L
CTD Gene:55870 ASH1L
dbSNP Gene:55870 ASH1L
ENSEMBL:ENSG00000116539 ASH1L
HGNC:19088 ASH1L
Monarch:55870 ASH1L
NCBI Gene:55870 ASH1L
OMIM:607999 ASH1L
UCSC:Q9NR48 ASH1L
Reference Transcript
RefSeq:XM_017001784.1 ASH1L
RefSeq:XM_006711450.3 ASH1L
RefSeq:XM_006711451.3 ASH1L
RefSeq:XM_017001785.1 ASH1L
RefSeq:NM_018489.2 ASH1L
Other Identifiers
11739569_at
11739570_at
11739571_at
11750039_a_at
16694188
218554_PM_s_at
218554_s_at
222667_PM_s_at
222667_s_at
226447_PM_at
226447_at
2437418
2437419
2437420
2437421
2437422
2437423
2437424
2437425
2437426
2437428
2437429
2437430
2437431
2437432
2437433
2437434
2437435
2437436
2437437
2437439
2437441
2437442
2437443
2437444
2437445
2437446
2437451
2437457
2437464
2437472
2437473
2437474
2437486
2437487
2437496
2437497
2437498
2437503
2437514
2437610
2437612
2437618
2437619
51982_at
55870
56170_at
7920766
A_23_P63083
A_24_P367666
A_33_P3402725
GE62408
GE63073
GE749133
GO:0000165
GO:0001501
GO:0002674
GO:0003677
GO:0003682
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005794
GO:0005923
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006366
GO:0006954
GO:0007018
GO:0007338
GO:0008168
GO:0009791
GO:0010468
GO:0016740
GO:0022414
GO:0030317
GO:0032259
GO:0042054
GO:0042800
GO:0043226
GO:0043409
GO:0045944
GO:0046697
GO:0046872
GO:0046974
GO:0046975
GO:0048733
GO:0048856
GO:0048870
GO:0050728
GO:0061038
GO:0140096
GO:0140938
GO:0140947
GO:0140948
GO:0140955
GO:1903699
GO:1903709
HMNXSV003001758
HMNXSV003005999
HMNXSV003053725
Hs.102652.0.S1_3p_a_at
Hs.38694.0.A1_3p_at
ILMN_1782032
PH_hs_0040129
TC01003315.hg
g8922080_3p_a_at
Participates
as a member of
WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Homo sapiens)
Inferred To
Ash1l [nucleoplasm]
(Mus musculus)
Ash1l [nucleoplasm]
(Rattus norvegicus)
ASH1L [nucleoplasm]
(Bos taurus)
ASH1L [nucleoplasm]
(Canis familiaris)
ASH1L [nucleoplasm]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
2648
OpenTargets
ENSG00000116539
ENSEMBL
ENSP00000504629
,
ENST00000392403
,
ENST00000678117
,
ENSP00000503265
,
ENST00000368346
,
ENSP00000357330
,
ENST00000677213
,
ENSP00000503315
,
ENSP00000376204
,
ENST00000679097
IntEnz
2.1.1.359
,
2.1.1.367
HPA
ENSG00000116539-ASH1L
PRO
Q9NR48
Pharos - Targets
Q9NR48
Orphanet
ASH1L
GlyGen
Q9NR48
PDB
6X0P
,
6AGO
,
7Y0I
,
3OPE
,
6INE
,
4YNP
,
4YPA
,
3MQM
,
6WZW
,
4YNM
,
4YPU
,
4YPE
HMDB Protein
HMDBP09007
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.553
2
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