Oligomerization of BAX at the mitochondrial membrane

Stable Identifier
R-HSA-114275
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
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Oligomerization of BAX at the mitochondrial membrane
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Once integrated in the outer mitochondrial membrane, BAX forms oligomeric complexes which play an important role in cytochrome C release (Antonsson et al. 2001)

Literature References
PubMed ID Title Journal Year
11136736 Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells.

Martinou, JC, Antonsson, B, Montessuit, S, Sanchez, B

J Biol Chem 2001
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Orthologous Events
Oligomerization of BAX at the mitochondrial membrane (Bos taurus)
Oligomerization of BAX at the mitochondrial membrane (Caenorhabditis elegans)
Oligomerization of BAX at the mitochondrial membrane (Canis familiaris)
Oligomerization of BAX at the mitochondrial membrane (Danio rerio)
Oligomerization of BAX at the mitochondrial membrane (Mus musculus)
Oligomerization of BAX at the mitochondrial membrane (Rattus norvegicus)
Created
Hardwick, JM  (2004-08-09)
Tsujimoto, Y  (2004-08-09)
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