Oligomerization of BAX at the mitochondrial membrane

Stable Identifier
R-HSA-114275
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Oligomerization of BAX at the mitochondrial membrane
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Once integrated in the outer mitochondrial membrane, BAX forms oligomeric complexes which play an important role in cytochrome C release (Antonsson et al. 2001)

Literature References
PubMed ID Title Journal Year
11136736 Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells.

Antonsson, B, Montessuit, S, Sanchez, B, Martinou, JC

J Biol Chem 2001
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
Oligomerization of BAX at the mitochondrial membrane (Bos taurus)
Oligomerization of BAX at the mitochondrial membrane (Canis familiaris)
Oligomerization of BAX at the mitochondrial membrane (Danio rerio)
Oligomerization of BAX at the mitochondrial membrane (Mus musculus)
Oligomerization of BAX at the mitochondrial membrane (Rattus norvegicus)
Oligomerization of BAX at the mitochondrial membrane (Sus scrofa)
Oligomerization of BAX at the mitochondrial membrane (Xenopus tropicalis)
Created
Hardwick, JM  (2004-08-09)
Tsujimoto, Y  (2004-08-09)