As a result of binding to Bid, Bax oligomerizes and integrates in the outer mitochondrial membrane, triggering cytochrome c release. Bax mitochondrial membrane insertion triggered by Bid may represent a key step in pathways leading to apoptosis (Eskes et al., 2000).
Roucou, X, Montessuit, S, Antonsson, B, Martinou, JC
Antonsson, B, Montessuit, S, Sanchez, B, Martinou, JC
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