As a result of binding to Bid, Bax oligomerizes and integrates in the outer mitochondrial membrane, triggering cytochrome c release. Bax mitochondrial membrane insertion triggered by Bid may represent a key step in pathways leading to apoptosis (Eskes et al., 2000).
Martinou, JC, Antonsson, B, Montessuit, S, Sanchez, B
Roucou, X, Martinou, JC, Antonsson, B, Montessuit, S
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