Oligomerization of BAK at the mitochondrial membrane

Stable Identifier
R-HSA-114263
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Once activated BAK insterts in the outer mitochondrial membrane, it oligomerizes and these oligomeric BAK complexes are important for the cytochrome C efflux (Ruffolo and Shore 2003).

Literature References
PubMed ID Title Journal Year
12721291 BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization

Ruffolo, SC, Shore, GC

J Biol Chem 2003
Participants
Participant Of
Orthologous Events
Created