Oligomerization of BAK at the mitochondrial membrane

Stable Identifier
R-HSA-114263
Type
Reaction [binding]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
ReviewStatus
5/5
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Oligomerization of BAK at the mitochondrial membrane
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Once activated BAK insterts in the outer mitochondrial membrane, it oligomerizes and these oligomeric BAK complexes are important for the cytochrome C efflux (Ruffolo and Shore 2003).

Literature References
PubMed ID Title Journal Year
12721291 BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization

Shore, GC, Ruffolo, SC

J Biol Chem 2003
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Created
Hardwick, JM  (2004-08-09)
Tsujimoto, Y  (2004-08-09)
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