Reactome | (d)ADP + ADP <=> (d)AMP + ATP (AK1)

(d)ADP + ADP <=> (d)AMP + ATP (AK1)

Stable Identifier

R-HSA-110141

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

Synonyms

2 ADP => AMP + ATP, dADP + ADP => dAMP + ATP

ReviewStatus

5/5

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Cytosolic adenylate kinase 1 (AK1) catalyzes the reversible reactions of ADP and dADP with ADP to form AMP and dAMP respectively, plus ATP (Tsuboi 1978; Matsuura et al. 1989).

Literature References

PubMed ID	Title	Journal	Year
211388	AMP (dAMP) kinase from human erythrocytes Tsuboi, KK	Methods Enzymol	1978
2542324	Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinase. Matsuura, S, Igarashi, M, Tanizawa, Y, Yamada, M, Kishi, F, Kajii, T, Fujii, H, Miwa, S, Sakurai, M, Nakazawa, A	J Biol Chem	1989