(d)AMP + ATP <=> (d)ADP + ADP (AK1)

Stable Identifier
R-HSA-74220
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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(d)AMP + ATP <=> (d)ADP + ADP (AK1)
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Cytosolic adenylate kinase 1 (AK1) catalyzes the reversible reactions of AMP and dAMP with ATP to form ADP and dADP respectively, plus ADP (Tsuboi 1978; Matsuura et al. 1989).
Literature References
PubMed ID Title Journal Year
211388 AMP (dAMP) kinase from human erythrocytes

Tsuboi, KK

Methods Enzymol 1978
2542324 Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinase.

Kajii, T, Matsuura, S, Miwa, S, Igarashi, M, Yamada, M, Fujii, H, Tanizawa, Y, Sakurai, M, Kishi, F, Nakazawa, A

J Biol Chem 1989
Participants
Input
Output
Participates
as an event of
Catalyst Activity

adenylate kinase activity of Adenylate Kinase [cytosol]

Physical Entity
Adenylate Kinase [cytosol] (Homo sapiens)
Activity
adenylate kinase activity (GO:0004017)
Orthologous Events
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Bos taurus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Caenorhabditis elegans)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Canis familiaris)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Drosophila melanogaster)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Gallus gallus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Mus musculus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Rattus norvegicus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Sus scrofa)
Cross References
Rhea
Created
Jassal, B  (2003-07-17)
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