Reactome | (d)AMP + ATP <=> (d)ADP + ADP (AK1)

(d)AMP + ATP <=> (d)ADP + ADP (AK1)

Stable Identifier

R-HSA-74220

Type

Reaction

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic adenylate kinase 1 (AK1) catalyzes the reversible reactions of AMP and dAMP with ATP to form ADP and dADP respectively, plus ADP (Tsuboi 1978; Matsuura et al. 1989).

Literature References

PubMed ID	Title	Journal	Year
211388	AMP (dAMP) kinase from human erythrocytes Tsuboi, KK	Methods Enzymol	1978
2542324	Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinase. Kajii, T, Matsuura, S, Miwa, S, Igarashi, M, Yamada, M, Fujii, H, Tanizawa, Y, Sakurai, M, Kishi, F, Nakazawa, A	J Biol Chem	1989