Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MAFF [nucleoplasm]
Stable Identifier
R-HSA-1008261
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transcription factor MAFF, MAFF_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
Expression of globin genes under control of the beta globin control region (Homo sapiens)
NF-E2:Promoter region of beta-globin [nucleoplasm] (Homo sapiens)
NF-E2 [nucleoplasm] (Homo sapiens)
Small Maf family members [nucleoplasm] (Homo sapiens)
MAFF [nucleoplasm] (Homo sapiens)
NFE2 binds the beta globin locus control region (Homo sapiens)
NF-E2 [nucleoplasm] (Homo sapiens)
Small Maf family members [nucleoplasm] (Homo sapiens)
MAFF [nucleoplasm] (Homo sapiens)
NF-E2:Promoter region of beta-globin [nucleoplasm] (Homo sapiens)
NF-E2 [nucleoplasm] (Homo sapiens)
Small Maf family members [nucleoplasm] (Homo sapiens)
MAFF [nucleoplasm] (Homo sapiens)
NFE2 is a heterodimer (Homo sapiens)
NF-E2 [nucleoplasm] (Homo sapiens)
Small Maf family members [nucleoplasm] (Homo sapiens)
MAFF [nucleoplasm] (Homo sapiens)
Small Maf family members [nucleoplasm] (Homo sapiens)
MAFF [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULX9 MAFF
Gene Names
MAFF
Chain
chain:1-164
Reference Genes
BioGPS Gene:23764 MAFF
COSMIC (genes):MAFF MAFF
CTD Gene:23764 MAFF
dbSNP Gene:23764 MAFF
ENSEMBL:ENSG00000185022 MAFF
HGNC:6780 MAFF
Monarch:23764 MAFF
NCBI Gene:23764 MAFF
OMIM:604877 MAFF
UCSC:Q9ULX9 MAFF
Reference Transcript
RefSeq:NM_001161573.1 MAFF
RefSeq:NM_001161572.1 MAFF
RefSeq:NM_012323.3 MAFF
RefSeq:NM_001161574.1 MAFF
Other Identifiers
11726611_x_at
11751684_a_at
16930051
205193_PM_at
205193_at
23764
36711_PM_at
36711_at
3945229
3945230
3945236
3945237
3945238
3945239
3945240
3945241
3945242
3945243
8073007
A_23_P103110
GE56058
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0001701
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005739
GO:0006355
GO:0006357
GO:0007567
GO:0022414
GO:0030154
GO:0035914
GO:0043226
GO:0043565
GO:0045604
GO:0045944
GO:0048856
GO:0090575
GO:0140110
GO:1990837
HMNXSV003045958
ILMN_1680139
ILMN_1700413
ILMN_2241168
ILMN_2322375
PH_hs_0026407
TC22000297.hg
g6912489_3p_s_at
Participates
as a member of
Small Maf family members [nucleoplasm] (Homo sapiens)
Inferred To
maf-S [nucleoplasm]
(Drosophila melanogaster)
Maff [nucleoplasm]
(Mus musculus)
Maff [nucleoplasm]
(Rattus norvegicus)
maff [nucleoplasm]
(Danio rerio)
maff [nucleoplasm]
(Xenopus tropicalis)
MAFF [nucleoplasm]
(Bos taurus)
MAFF [nucleoplasm]
(Canis familiaris)
MAFF [nucleoplasm]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000441482
,
ENST00000538999
,
ENSP00000442060
,
ENST00000538320
,
ENST00000426621
,
ENST00000338483
,
ENSP00000388882
,
ENST00000407965
,
ENSP00000384094
,
ENSP00000345393
OpenTargets
ENSG00000185022
HPA
ENSG00000185022-MAFF
PRO
Q9ULX9
Pharos - Targets
Q9ULX9
GlyGen
Q9ULX9
HMDB Protein
HMDBP10749
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16236 NFE2L2
13
p-S40-NFE2L2 [nucleoplasm]
(R-HSA-9715109)
p-S,T-NFE2L2 [nucleoplasm]
(R-HSA-9715110)
p-S40-NFE2L2 [cytosol]
(R-HSA-8932290)
p-S,T-NFE2L2 [cytosol]
(R-HSA-8932311)
NFE2L2 [cytosol]
(R-HSA-201566)
p-S,T-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760033)
p-S40-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760018)
ub-NFE2L2 [cytosol]
(R-HSA-9758077)
ub-p-S335, S338,T-NFE2L2 [nucleoplasm]
(R-HSA-9762055)
ub-p-S40, S335, S338- NFE2L2 [nucleoplasm]
(R-HSA-9762058)
p-S344, S347,T-NFE2L2 [nucleoplasm]
(R-HSA-9762048)
p-S40, S344, S347- NFE2L2 [nucleoplasm]
(R-HSA-9762050)
p-S,T,S558-NFE2L2 [nucleoplasm]
(R-HSA-9795736)
0.77
6
UniProt:O14867 BACH1
5
BACH1 [nucleoplasm]
(R-HSA-9707688)
BACH1 [cytosol]
(R-HSA-9708429)
PolyUb-BACH1 [nucleoplasm]
(R-HSA-9708486)
p-Y483 BACH1 [nucleoplasm]
(R-HSA-9762202)
p-Y483 BACH1 [cytosol]
(R-HSA-9762206)
0.759
6
UniProt:P97302
5
phospho-Bach1 [cytosol]
(R-MMU-9762206)
phospho-Bach1 [nucleoplasm]
(R-MMU-9762202)
Bach1 [nucleoplasm]
(R-MMU-9708486)
Bach1 [cytosol]
(R-MMU-9708429)
Bach1 [nucleoplasm]
(R-MMU-9707688)
0.564
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text