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CUL3 [cytosol]
Stable Identifier
R-GGA-975979
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
E1BYQ3
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Gallus gallus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Gallus gallus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
RHOBTB3 ATPase cycle (Gallus gallus)
RHOBTB3 binds interacting proteins at trans-Golgi network (Gallus gallus)
RHOBTB3 interacting proteins [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
RHOBTB3:ATP:RHOBTB3 interacting proteins [trans-Golgi network membrane] (Gallus gallus)
RHOBTB3 interacting proteins [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RHOBTB GTPase Cycle (Gallus gallus)
RHOBTB1 GTPase cycle (Gallus gallus)
RHOBTB1 binds interacting proteins at the endosome membrane (Gallus gallus)
RHOBTB1 interacting proteins [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Gallus gallus)
RHOBTB1 interacting proteins [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
RHOBTB2 GTPase cycle (Gallus gallus)
RHOBTB2 binds interacting proteins at the endosome membrane (Gallus gallus)
RHOBTB2 interacting proteins [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
RHOBTB2:GTP:RHOBTB2 interacting proteins [endosome membrane] (Gallus gallus)
RHOBTB2 interacting proteins [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Signaling by WNT (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Degradation of DVL (Gallus gallus)
DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Gallus gallus)
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Gallus gallus)
DVL:CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
Ubiquitinated DVL is degraded by the proteasome (Gallus gallus)
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
ub-DVL:CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
CUL3 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BYQ3
Reference Genes
ENSEMBL:ENSGALG00000005108
UCSC:E1BYQ3
Participates
as a member of
RHOBTB1 interacting proteins [cytosol] (Gallus gallus)
RHOBTB2 interacting proteins [cytosol] (Gallus gallus)
RHOBTB3 interacting proteins [cytosol] (Gallus gallus)
as a component of
CUL3:KLHL12:RBX1 [cytosol] (Gallus gallus)
RBX1:CUL3:BTB [cytosol] (Gallus gallus)
Other forms of this molecule
G76-NEDD8-K712-CUL3 [cytosol]
CUL3 [nucleoplasm]
Inferred From
CUL3 [cytosol]
(Homo sapiens)
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