Reactome | ATP6V1D [cytosol]

ATP6V1D [cytosol]

Stable Identifier

R-GGA-912597

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

ATP6V1D, A0A1L1S0D5

Locations in the PathwayBrowser

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Cellular responses to external stimuli (Gallus gallus)

- Cellular responses to stress (Gallus gallus)
  - Amino acids regulate mTORC1 (Gallus gallus)
    - RRAGA,B exchanges GDP for GTP (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - RRAGA,B hydrolyzes GTP (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - RRAGC,D exchanges GTP for GDP (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - RRAGC,D hydrolyzes GTP (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - mTORC1 binds RHEB:GTP (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
    - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Signaling by Receptor Tyrosine Kinases (Gallus gallus)
  - Signaling by Insulin receptor (Gallus gallus)
    - Insulin receptor recycling (Gallus gallus)
      - Endosome acidification (Gallus gallus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Gallus gallus)
        
        V-ATPase [endosome membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)

Transport of small molecules (Gallus gallus)

- Iron uptake and transport (Gallus gallus)
  - Transferrin endocytosis and recycling (Gallus gallus)
    - Acidification of Tf:TfR1 containing endosome (Gallus gallus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Gallus gallus)
        
        V-ATPase [endosome membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1D [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1L1S0D5

Gene Names

ATP6V1D

Reference Genes

BioGPS Gene:423280 ATP6V1D

ENSEMBL:ENSGALG00000009570

KEGG Gene (Gallus gallus):423280 ATP6V1D

Monarch:423280 ATP6V1D

NCBI Gene:423280 ATP6V1D

Reference Transcript

RefSeq:NM_001277439.1 ATP6V1D

Other Identifiers

423280

GO:0003674

GO:0005575

GO:0005622

GO:0005813

GO:0005815

GO:0005856

GO:0005929

GO:0006810

GO:0006811

GO:0008150

GO:0016020

GO:0022607

GO:0022857

GO:0032991

GO:0033176

GO:0042626

GO:0043226

GO:0046961

GO:0055085

GO:0060271

GO:0061512

GO:1902600

GT_A_87_P021909

GT_A_87_P085021

Gga.8201.1.S1_at

Participant Of

hasComponent

ATP6V1 [cytosol]

Other forms of this molecule

ATP6V1D [plasma membrane]

ATP6V1D [specific granule membrane]

Inferred From

ATP6V1D [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001264368.1

OpenTargets

ENSG00000100554

Ensembl

ENSGALT00000088383, ENSGALG00000009570, ENSGALP00000064593

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