Reactome | ATP6V1C2 [cytosol]

ATP6V1C2 [cytosol]

Stable Identifier

R-GGA-912573

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

ATP6V1C2, A0A8V0XGD7

Locations in the PathwayBrowser

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Cellular responses to stimuli (Gallus gallus)

- Cellular responses to stress (Gallus gallus)
  - Cellular response to starvation (Gallus gallus)
    - Amino acids regulate mTORC1 (Gallus gallus)
      - RRAGA,B exchanges GDP for GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
      - RRAGA,B hydrolyzes GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
      - RRAGC,D exchanges GTP for GDP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
      - RRAGC,D hydrolyzes GTP (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Gallus gallus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Gallus gallus)
        
        v-ATPase [lysosomal membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Signaling by Receptor Tyrosine Kinases (Gallus gallus)
  - Signaling by Insulin receptor (Gallus gallus)
    - Insulin receptor recycling (Gallus gallus)
      - Endosome acidification (Gallus gallus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Gallus gallus)
        
        V-ATPase [endosome membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)

Transport of small molecules (Gallus gallus)

- Iron uptake and transport (Gallus gallus)
  - Transferrin endocytosis and recycling (Gallus gallus)
    - Acidification of Tf:TfR1 containing endosome (Gallus gallus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Gallus gallus)
        
        V-ATPase [endosome membrane] (Gallus gallus)
        
        ATP6V1 [cytosol] (Gallus gallus)
        
        ATP6V1C [cytosol] (Gallus gallus)
        
        ATP6V1C2 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0XGD7

Gene Names

ATP6V1C2

Reference Genes

BioGPS Gene:421939 ATP6V1C2

ENSEMBL:ENSGALG00010002590.1

Monarch:421939 ATP6V1C2

NCBI Gene:421939 ATP6V1C2

UCSC:A0A8V0XGD7 ATP6V1C2

Reference Transcript

Other Identifiers

421939

GO:0000221

GO:0006811

GO:0015078

GO:0030177

GO:0033180

GO:0042802

GO:0046961

GO:0055085

GO:1902600

GT_A_87_P025405

GgaAffx.10526.2.S1_s_at

Participates

as a member of

ATP6V1C [cytosol] (Gallus gallus)

Inferred From

ATP6V1C2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_025004712.2, XP_025004711.2, XP_025004710.2, XP_025004709.2, XP_025004708.2

ENSEMBL

ENSGALP00010003720, ENSGALT00010005976, ENSGALG00010002590

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