Reactome | PDE1B [cytosol]

PDE1B [cytosol]

Stable Identifier

R-GGA-9014908

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

activated PDE1B, A0A3Q2U726

Locations in the PathwayBrowser

Expand all

Hemostasis (Gallus gallus)

- Platelet homeostasis (Gallus gallus)
  - Nitric oxide stimulates guanylate cyclase (Gallus gallus)
    - cGMP effects (Gallus gallus)
      - cGMP is degraded by PDEs (Gallus gallus)
        
        cGMP phosphodiesterases [cytosol] (Gallus gallus)
        
        Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Intracellular signaling by second messengers (Gallus gallus)
  - DAG and IP3 signaling (Gallus gallus)
    - CaM pathway (Gallus gallus)
      - Calmodulin induced events (Gallus gallus)
        
        Cam-PDE 1 activation (Gallus gallus)
        
        Calmodulin activates Cam-PDE 1 (Gallus gallus)
        
        PDE1 dimers [cytosol] (Gallus gallus)
        
        activated PDE1B dimer [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)
        
        activated PDE1 dimers [cytosol] (Gallus gallus)
        
        activated PDE1B dimer [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)
        
        cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)
        
        activated PDE1 dimers [cytosol] (Gallus gallus)
        
        activated PDE1B dimer [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)
- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Opioid Signalling (Gallus gallus)
        
        G-protein mediated events (Gallus gallus)
        
        PLC beta mediated events (Gallus gallus)
        
        Ca-dependent events (Gallus gallus)
        
        CaM pathway (Gallus gallus)
        
        Calmodulin induced events (Gallus gallus)
        
        Cam-PDE 1 activation (Gallus gallus)
        
        Calmodulin activates Cam-PDE 1 (Gallus gallus)
        
        PDE1 dimers [cytosol] (Gallus gallus)
        
        activated PDE1B dimer [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)
        
        activated PDE1 dimers [cytosol] (Gallus gallus)
        
        activated PDE1B dimer [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)
        
        cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)
        
        activated PDE1 dimers [cytosol] (Gallus gallus)
        
        activated PDE1B dimer [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)
    - G alpha (s) signalling events (Gallus gallus)
      - cAMP degradation by Phosphodiesterases (Gallus gallus)
        
        cAMP PDEs [cytosol] (Gallus gallus)
        
        Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Gallus gallus)
        
        PDE1B [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A3Q2U726

Gene Names

PDE1B

Reference Genes

BioGPS Gene:777528 PDE1B

ENSEMBL:ENSGALG00010025658.1

Monarch:777528 PDE1B

NCBI Gene:777528 PDE1B

UCSC:A0A3Q2U726 PDE1B

Reference Transcript

Other Identifiers

777528

GO:0001975

GO:0004114

GO:0004115

GO:0004117

GO:0005737

GO:0005829

GO:0007165

GO:0007626

GO:0008081

GO:0008542

GO:0016787

GO:0030154

GO:0030224

GO:0036006

GO:0042420

GO:0042428

GO:0043025

GO:0046872

GO:0047555

GO:0048101

GO:0097011

GO:0141162

GT_A_87_P308242

GT_Sp_Chicken_CN224654_4615

GT_Sp_LOC777528_131

GT_Sp_LOC777528_132

GT_Sp_LOC777528_140

Participates

as a member of

Phosphodiesterases, dual (cAMP, cGMP) activity [cytosol] (Gallus gallus)

as a component of

activated PDE1B dimer [cytosol] (Gallus gallus)

Inferred From

activated PDE1B [cytosol] (Homo sapiens)

PDE1B [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_040549900.1, XP_040549901.1, XP_025001376.1, XP_025001377.1

ENSEMBL

ENSGALP00010038728, ENSGALT00010062637, ENSGALG00010025658