Reactome | CD3D [clathrin-coated endocytic vesicle membrane]

CD3D [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-GGA-8869079

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

CD3D, A0A8V0ZU77

Locations in the PathwayBrowser

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Vesicle-mediated transport (Gallus gallus)

- Membrane Trafficking (Gallus gallus)
  - Clathrin-mediated endocytosis (Gallus gallus)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
    - RAB5 and GAPVD1 bind AP-2 (Gallus gallus)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)
        
        CD3D [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0ZU77

Gene Names

CD3D

Reference Genes

ENSEMBL:ENSGALG00010023743.1

UCSC:A0A8V0ZU77 CD3D

Other Identifiers

396518

GO:0002376

GO:0004888

GO:0007166

GO:0009897

GO:0016020

GO:0042105

GO:0045059

GT_A_87_P055316

GT_A_87_P223853

Gga.998.2.S1_a_at

Participates

as a member of

AP-2 dileucine-containing cargo [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

Other forms of this molecule

CD3D [clathrin-coated endocytic vesicle membrane]

CD3D [plasma membrane]

phospho-CD3D [plasma membrane]

Inferred From

CD3D [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSGALT00010057897, ENSGALG00010023743, ENSGALP00010035127

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