Reactome | LOC100858177 [extracellular region]

LOC100858177 [extracellular region]

Stable Identifier

R-GGA-877351

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

extracellular region

Synonyms

IFNB1, A0A8V0YE55

Locations in the PathwayBrowser

Expand all

Immune System (Gallus gallus)

- Cytokine Signaling in Immune system (Gallus gallus)
  - Interferon Signaling (Gallus gallus)
    - Interferon alpha/beta signaling (Gallus gallus)
      - Activation of JAK kinases (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Formation of p-STAT1 homodimer (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - IFN alpha/beta binds to IFNAR2 (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Phosphorylation of INFAR1 by TYK2 (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Phosphorylation of STAT2 (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Recruitment of IFNAR1 (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Recruitment of STAT2 to p-IFNAR1 (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Regulation of IFNA/IFNB signaling (Gallus gallus)
        
        Dephosphorylation of JAK1 by SHP1 (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        Dephosphorylation of STAT1 by SHP2 (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        Dephosphorylation of TYK2 by PTP1B (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
      - Release of p-STAT2:p-STAT1 dimer (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Gallus gallus)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Gallus gallus)
        
        Homologues of IFNB1 [extracellular region] (Gallus gallus)
        
        LOC100858177 [extracellular region] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0YE55

Gene Names

LOC100858177

Reference Genes

BioGPS Gene:100858177 LOC100858177

ENSEMBL:ENSGALG00010012356.1

Monarch:100858177 LOC100858177

NCBI Gene:100858177 LOC100858177

UCSC:A0A8V0YE55 LOC100858177

Reference Transcript

Other Identifiers

100858177

GO:0002250

GO:0002286

GO:0002312

GO:0002323

GO:0002376

GO:0005125

GO:0005126

GO:0005132

GO:0005576

GO:0005615

GO:0006950

GO:0006952

GO:0006955

GO:0006959

GO:0009615

GO:0043330

GO:0048018

GO:0051607

GO:0060337

GO:0098542

GO:0098772

GT_A_87_P059656

GT_A_87_P091555

GT_Xhyb_LOC100859032_1000

GT_Xhyb_LOC100859032_991

GT_Xhyb_LOC100859032_999

GT_Xhyb_LOC768614_1001

GT_Xhyb_LOC768614_1002

GT_Xhyb_LOC768614_1010

Gga.801.1.S1_at

Participates

as a member of

Homologues of IFNB1 [extracellular region] (Gallus gallus)

Other forms of this molecule

LOC100858177 [extracellular region]

Inferred From

IFNB1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_040512536.1, XP_046792182.1

ENSEMBL

ENSGALG00010012356, ENSGALT00010029588, ENSGALP00010017209

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