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EIF4G1 [cytosol]
Stable Identifier
R-GGA-72584
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
EIF4G1, A0A8V0Z8Y0
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Gallus gallus)
Deadenylation-dependent mRNA decay (Gallus gallus)
Deadenylation of mRNA (Gallus gallus)
CCR4-NOT complex deadenylates mRNA (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Partially Deadenylated mRNA Complex [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
PAN2-PAN3 complex partially deadenylates mRNA (Gallus gallus)
Partially Deadenylated mRNA Complex [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Translatable mRNA Complex [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
PARN deadenylates mRNA (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Partially Deadenylated mRNA Complex [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Nonsense-Mediated Decay (NMD) (Gallus gallus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
mRNA Cleaved by SMG6 [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Regulation of mRNA stability by proteins that bind AU-rich elements (Gallus gallus)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Gallus gallus)
AUF1 (hnRNP D0) is ubiquitinylated (Gallus gallus)
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Translation (Gallus gallus)
Eukaryotic Translation Initiation (Gallus gallus)
Cap-dependent Translation Initiation (Gallus gallus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Gallus gallus)
Translation initiation complex formation (Gallus gallus)
Formation of translation initiation complexes containing mRNA that does not circularize (Gallus gallus)
48S complex [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Gallus gallus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Ribosomal scanning and start codon recognition (Gallus gallus)
Ribosomal scanning (Gallus gallus)
48S complex [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Start codon recognition (Gallus gallus)
48S complex [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
MTOR signalling (Gallus gallus)
mTORC1-mediated signalling (Gallus gallus)
Phosphorylation and activation of eIF4G by activated S6K1 (Gallus gallus)
EIF4G1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0Z8Y0
Gene Names
EIF4G1
Reference Genes
BioGPS Gene:424953 EIF4G1
ENSEMBL:ENSGALG00010017540.1
KEGG:gga:424953 EIF4G1
Monarch:424953 EIF4G1
NCBI Gene:424953 EIF4G1
UCSC:A0A8V0Z8Y0 EIF4G1
Reference Transcript
RefSeq:XM_046898836.1 EIF4G1
RefSeq:XM_015291536.4 EIF4G1
RefSeq:XM_046898834.1 EIF4G1
RefSeq:XM_040705696.2 EIF4G1
RefSeq:XM_046898835.1 EIF4G1
RefSeq:XM_040705698.2 EIF4G1
RefSeq:XM_015291534.4 EIF4G1
RefSeq:XM_015291535.4 EIF4G1
RefSeq:XM_040705697.2 EIF4G1
RefSeq:XM_025153664.3 EIF4G1
RefSeq:XM_015291528.4 EIF4G1
RefSeq:XM_046898832.1 EIF4G1
RefSeq:XM_046898833.1 EIF4G1
Other Identifiers
424953
GO:0001662
GO:0003723
GO:0003729
GO:0003743
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005840
GO:0006412
GO:0006413
GO:0006417
GO:0006446
GO:0008135
GO:0008190
GO:0010494
GO:0010507
GO:0016281
GO:0030182
GO:0030307
GO:0031047
GO:0031669
GO:0035278
GO:0036493
GO:0045666
GO:0051247
GO:0097009
GO:1900087
GO:1904377
GO:1905537
GO:1905606
GT_A_87_P077701
GgaAffx.5365.1.S1_s_at
Participates
as a component of
AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] (Gallus gallus)
mRNA Cleaved by SMG6 [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] (Gallus gallus)
mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] (Gallus gallus)
Translatable mRNA Complex [cytosol] (Gallus gallus)
Partially Deadenylated mRNA Complex [cytosol] (Gallus gallus)
eIF4F [cytosol] (Gallus gallus)
as an output of
PARN deadenylates mRNA (Gallus gallus)
CCR4-NOT complex deadenylates mRNA (Gallus gallus)
as an input of
Phosphorylation and activation of eIF4G by activated S6K1 (Gallus gallus)
Other forms of this molecule
phospho-EIF4G1 [cytosol]
Inferred From
EIF4G1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_015147014.2
,
XP_046754789.1
,
XP_046754788.1
,
XP_015147022.2
,
XP_040561632.1
,
XP_015147021.2
,
XP_015147020.2
,
XP_046754790.1
,
XP_025009432.2
,
XP_040561631.1
,
XP_046754791.1
,
XP_040561630.1
,
XP_046754792.1
ENSEMBL
ENSGALP00010024889
,
ENSGALT00010042399
,
ENSGALG00010017540
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