Reactome | OGDH [mitochondrial matrix]

OGDH [mitochondrial matrix]

Stable Identifier

R-GGA-69981

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

mitochondrial matrix

Synonyms

OGDH, A0A8V0Z707

Locations in the PathwayBrowser

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Metabolism (Gallus gallus)

- Aerobic respiration and respiratory electron transport (Gallus gallus)
  - Citric acid cycle (TCA cycle) (Gallus gallus)
    - OGDH complex synthesizes succinyl-CoA from 2-OG (Gallus gallus)
      - DLD dimer dehydrogenates dihydrolipoyl (Gallus gallus)
        
        OGDH complex [mitochondrial matrix] (Gallus gallus)
        
        OGDH dimer [mitochondrial matrix] (Gallus gallus)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
        
        OGDH [mitochondrial matrix] (Gallus gallus)
      - DLST transfers succinyl to CoA (Gallus gallus)
        
        OGDH complex [mitochondrial matrix] (Gallus gallus)
        
        OGDH dimer [mitochondrial matrix] (Gallus gallus)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
        
        OGDH [mitochondrial matrix] (Gallus gallus)
      - OGDH dimer decarboxylates 2-OG (Gallus gallus)
        
        OGDH complex [mitochondrial matrix] (Gallus gallus)
        
        OGDH dimer [mitochondrial matrix] (Gallus gallus)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
        
        OGDH [mitochondrial matrix] (Gallus gallus)
        
        OGDH dimer [mitochondrial matrix] (Gallus gallus)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
        
        OGDH [mitochondrial matrix] (Gallus gallus)
- Metabolism of amino acids and derivatives (Gallus gallus)
  - Glyoxylate metabolism and glycine degradation (Gallus gallus)
    - Glycine degradation (Gallus gallus)
      - DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Gallus gallus)
        
        OGDH complex [mitochondrial matrix] (Gallus gallus)
        
        OGDH dimer [mitochondrial matrix] (Gallus gallus)
        
        alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)
        
        OGDH [mitochondrial matrix] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0Z707

Gene Names

OGDH

Reference Genes

BioGPS Gene:426429 OGDH

ENSEMBL:ENSGALG00010018519.1

Monarch:426429 OGDH

NCBI Gene:426429 OGDH

UCSC:A0A8V0Z707 OGDH

Reference Transcript

RefSeq:XM_015297480.4 OGDH

Other Identifiers

426429

GO:0004591

GO:0005634

GO:0005739

GO:0005759

GO:0006091

GO:0006096

GO:0006099

GO:0006103

GO:0006104

GO:0006790

GO:0016491

GO:0016624

GO:0021695

GO:0021756

GO:0021794

GO:0021860

GO:0022028

GO:0030976

GO:0045252

GO:0046872

GO:0048856

GO:0048870

GO:0055086

GO:0061034

GO:0120551

GO:1901135

GT_A_87_P036350

GT_A_87_P061561

GT_A_87_P215898

Gga.7238.1.S1_s_at

Gga.7238.2.S1_s_at

Participates

as a member of

Substrate of LONP1 (mitochondrial matrix) [mitochondrial matrix] (Gallus gallus)

as a component of

alpha-ketoglutarate dehydrogenase E1 holoenzyme [mitochondrial matrix] (Gallus gallus)

Inferred From

OGDH [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

XP_015152966.1

ENSEMBL

ENSGALT00010044811, ENSGALG00010018519, ENSGALP00010026733