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p-S166,S188-MDM2 dimer [nucleoplasm]
Stable Identifier
R-GGA-6804933
Type
Complex
Species
Gallus gallus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle Checkpoints (Gallus gallus)
G1/S DNA Damage Checkpoints (Gallus gallus)
p53-Dependent G1/S DNA damage checkpoint (Gallus gallus)
p53-Dependent G1 DNA Damage Response (Gallus gallus)
Stabilization of p53 (Gallus gallus)
MDM2 forms homo- or heterodimers (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
Regulation of TP53 Activity (Gallus gallus)
Regulation of TP53 Activity through Methylation (Gallus gallus)
MDM2 ubiquitinates JMY (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
Regulation of TP53 Activity through Phosphorylation (Gallus gallus)
MDM2 ubiquitinates DYRK2 (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
Regulation of TP53 Expression and Degradation (Gallus gallus)
Regulation of TP53 Degradation (Gallus gallus)
MDM2 forms homo- or heterodimers (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
MDM2 homodimers auto-ubiquitinate (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
Transcriptional regulation by RUNX3 (Gallus gallus)
Regulation of RUNX3 expression and activity (Gallus gallus)
MDM2 binds RUNX3 (Gallus gallus)
RUNX3:p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
MDM2 polyubiquitinates RUNX3 (Gallus gallus)
RUNX3:p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-MDM2 [nucleoplasm]
(Gallus gallus)
Participates
as an output of
MDM2 polyubiquitinates RUNX3 (Gallus gallus)
MDM2 forms homo- or heterodimers (Gallus gallus)
as an input of
MDM2 binds RUNX3 (Gallus gallus)
MDM2 homodimers auto-ubiquitinate (Gallus gallus)
as a component of
RUNX3:p-S166,S188-MDM2 dimer [nucleoplasm] (Gallus gallus)
Inferred From
p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4 [nucleoplasm]
(Homo sapiens)
p-S166,S188-MDM2 dimer [nucleoplasm]
(Homo sapiens)
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