Reactome | SOCS5 [cytosol]

SOCS5 [cytosol]

Stable Identifier

R-GGA-6788342

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

SOCS5, B2WUP1

Locations in the PathwayBrowser

Expand all

Immune System (Gallus gallus)

- Cytokine Signaling in Immune system (Gallus gallus)
  - Signaling by Interleukins (Gallus gallus)
    - Interleukin-4 and Interleukin-13 signaling (Gallus gallus)
      - SOCS5,(SOCS1) bind IL4RA (Gallus gallus)
        
        IL4:IL4R:JAK2:IL13RA:TYK2:SOCS5,(SOCS1) [plasma membrane] (Gallus gallus)
        
        SOCS5,(SOCS1) [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)
        
        SOCS5,(SOCS1) [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)

Metabolism of proteins (Gallus gallus)

- Post-translational protein modification (Gallus gallus)
  - Neddylation (Gallus gallus)
    - AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Gallus gallus)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL5-box protein [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)
      - NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Gallus gallus)
        
        CUL5-box protein [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Gallus gallus)
        
        CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL5-box protein [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)
      - CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL5-box protein [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Gallus gallus)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL5-box protein [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Gallus gallus)
        
        CUL5-box protein [cytosol] (Gallus gallus)
        
        SOCS5 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:B2WUP1

Gene Names

SOCS5

Reference Genes

BioGPS Gene:428570 SOCS5

ENSEMBL:ENSGALG00010018511.1

KEGG:gga:428570 SOCS5

Monarch:428570 SOCS5

NCBI Gene:428570 SOCS5

UCSC:B2WUP1 SOCS5

Reference Transcript

Other Identifiers

428570

GO:0005154

GO:0007173

GO:0007259

GO:0009968

GO:0016567

GO:0019221

GO:0030971

GO:0032436

GO:0032715

GO:0035556

GO:0045627

GO:0045629

GO:0050728

GO:0071404

GO:0071638

GO:0097699

GT_A_87_P011338

GT_A_87_P098011

GT_A_87_P229758

Gga.8142.1.S1_at

GgaAffx.20787.1.S1_at

GgaAffx.6294.1.S1_at

Participates

as a member of

Inferred From

SOCS5 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_046770276.1, XP_046770275.1, XP_046770278.1, XP_040553211.1, XP_046770274.1, XP_046770277.1, XP_040553212.1, NP_001120786.1

ENSEMBL

ENSGALT00010044797, ENSGALT00010044779, ENSGALT00010044788, ENSGALT00010044792, ENSGALT00010044793, ENSGALP00010026714, ENSGALP00010026710, ENSGALP00010026707, ENSGALP00010026705, ENSGALP00010026701, ENSGALP00010026704, ENSGALP00010026716, ENSGALP00010026719, ENSGALP00010026712, ENSGALP00010026715, ENSGALT00010044790, ENSGALT00010044794, ENSGALT00010044782, ENSGALT00010044785, ENSGALT00010044783, ENSGALG00010018511