Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PLCB2 [cytosol]
Stable Identifier
R-GGA-61695
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
A0A8V0ZVU8
Locations in the PathwayBrowser
Expand all
Metabolism (Gallus gallus)
Inositol phosphate metabolism (Gallus gallus)
Synthesis of IP3 and IP4 in the cytosol (Gallus gallus)
PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Gallus gallus)
PLCbz [cytosol] (Gallus gallus)
PLCB2:Ca2+ [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
Integration of energy metabolism (Gallus gallus)
Regulation of insulin secretion (Gallus gallus)
Acetylcholine regulates insulin secretion (Gallus gallus)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Gallus gallus)
PLC beta1,2,3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Gallus gallus)
PLC beta1,2,3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
Free fatty acids regulate insulin secretion (Gallus gallus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Gallus gallus)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Gallus gallus)
PLC beta1,2,3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Gallus gallus)
PLC beta1,2,3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
Activation of kainate receptors upon glutamate binding (Gallus gallus)
Presynaptic function of Kainate receptors (Gallus gallus)
Activation of GRIK3 homomer (Gallus gallus)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
Kainate receptor-glutamate-Gprotein complex [plasma membrane] (Gallus gallus)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Opioid Signalling (Gallus gallus)
G-protein mediated events (Gallus gallus)
PLC beta mediated events (Gallus gallus)
Inactivation of PLC beta (Gallus gallus)
Activated PLC beta 1/4 [plasma membrane] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PIP2 hydrolysis (Gallus gallus)
Activated PLC beta 1/4 [plasma membrane] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
G alpha (q) signalling events (Gallus gallus)
PLC-beta hydrolyses PIP2 to DAG and IP3 (Gallus gallus)
Activated PLC beta 1/4 [plasma membrane] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC-beta:G-alpha(q/11):DAG:IP3 [plasma membrane] (Gallus gallus)
Activated PLC beta 1/4 [plasma membrane] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC-beta:G-alpha(q/11):PIP2 [plasma membrane] (Gallus gallus)
Activated PLC beta 1/4 [plasma membrane] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
G-protein beta:gamma signalling (Gallus gallus)
G beta:gamma signalling through PLC beta (Gallus gallus)
Gbeta:gamma activation of PLC beta (Gallus gallus)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC beta-mediated PIP2 hydrolysis (Gallus gallus)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
Signaling by WNT (Gallus gallus)
Beta-catenin independent WNT signaling (Gallus gallus)
Ca2+ pathway (Gallus gallus)
Gbeta:gamma activation of PLC beta (Gallus gallus)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
PLC beta-mediated PIP2 hydrolysis (Gallus gallus)
G-protein beta-gamma:PLC beta 1/2/3 [plasma membrane] (Gallus gallus)
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLCB2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0ZVU8
Reference Genes
ENSEMBL:ENSGALG00010023305.1
UCSC:A0A8V0ZVU8
Other Identifiers
423014
GO:0004435
GO:0004629
GO:0005509
GO:0005737
GO:0006629
GO:0007165
GO:0007186
GO:0007200
GO:0008081
GO:0016042
GO:0016787
GO:0035556
GO:0046488
GO:0046872
GO:0048015
GO:0050877
GO:0050913
GO:0051209
GO:0055085
GO:0098992
GT_A_87_P157053
GT_A_87_P270288
GgaAffx.2978.1.S1_at
GgaAffx.2978.2.S1_s_at
GgaAffx.2978.3.S1_s_at
Participates
as a candidate of
PLC beta1,2,3 [cytosol] (Gallus gallus)
as a member of
PLC-beta 1/2/3 [cytosol] (Gallus gallus)
PLC-beta [cytosol] (Gallus gallus)
as a component of
PLCB2:Ca2+ [cytosol] (Gallus gallus)
Inferred From
PLCB2 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSGALP00010034547
,
ENSGALT00010056822
,
ENSGALG00010023305
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text