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IRF3 [cytosol]
Stable Identifier
R-GGA-450281
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
IRF7, Q90643
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Gallus gallus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Gallus gallus)
IRF3 [cytosol] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
IRF3 [cytosol] (Gallus gallus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
IRF3 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q90643 IRF3
Gene Names
IRF3
Chain
chain:1-491
Reference Genes
BioGPS Gene:396330 IRF3
KEGG:gga:396330 IRF3
Monarch:396330 IRF3
NCBI Gene:396330 IRF3
UCSC:Q90643 IRF3
Participates
as an input of
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Gallus gallus)
as a component of
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
Other forms of this molecule
IRF3 [mitochondrial outer membrane]
phosphorylated IRF3 [nucleoplasm]
phosphorylated IRF3 [cytosol]
IRF3 [cytosol]
phospho-IRF3 [nucleoplasm]
phospho-IRF3 [cytosol]
Inferred From
IRF3,IRF7 [cytosol]
(Homo sapiens)
IRF7 [cytosol]
(Homo sapiens)
Cross References
PRO
Q90643
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