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IRF3,IRF7 [cytosol]
Stable Identifier
R-HSA-450317
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF3-dependent IRF activation pathway (Homo sapiens)
Phosphorylation and release of IRF3/IRF7 (Homo sapiens)
viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane] (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
Recruitment of IRF3,IRF7 (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane] (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
TICAM1-dependent activation of IRF3/IRF7 (Homo sapiens)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex (Homo sapiens)
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Homo sapiens)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Homo sapiens)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
IRF3,IRF7 [cytosol] (Homo sapiens)
Participants
members
IRF3 [cytosol]
(Homo sapiens)
IRF7 [cytosol]
(Homo sapiens)
Participates
as a component of
activated TLR3:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Homo sapiens)
viral dsRNA:IFIH1, viral dsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3:2xTBK1,IKBKE:IRF3,IRF7 [mitochondrial outer membrane] (Homo sapiens)
as an input of
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR3 (Homo sapiens)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Homo sapiens)
Recruitment of IRF3,IRF7 (Homo sapiens)
Inferred To
irf7 [cytosol]
(Xenopus tropicalis)
IRF-3 [cytosol]
(Gallus gallus)
IRF3,IRF7 [cytosol]
(Bos taurus)
IRF3,IRF7 [cytosol]
(Mus musculus)
IRF3,IRF7 [cytosol]
(Rattus norvegicus)
IRF3,IRF7 [cytosol]
(Sus scrofa)
IRF3 [cytosol]
(Canis familiaris)
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