Reactome | adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate

adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate

Stable Identifier

R-GGA-421197

Type

Reaction [transition]

Species

Gallus gallus

Compartment

cytosol

ReviewStatus

5/5

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adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate

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Cytosolic ADSL catalyzes the cleavage of adenylosuccinate to form AMP and fumarate. The chicken ADSL gene has been cloned (Aimi et al. 1990) but its protein product has not been biochemically characterized and this reaction is inferred from its better-studied human counterpart.

Literature References

PubMed ID	Title	Journal	Year
2111814	Cloning of a cDNA encoding adenylosuccinate lyase by functional complementation in Escherichia coli Zalkin, H, Aimi, J, Williams, J, Badylak, J, Chen, ZD, Dixon, JE	J Biol Chem	1990