Reactome | ACTA1 [cytosol]

ACTA1 [cytosol]

Stable Identifier

R-GGA-390534

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

A0A8V0Y055

Locations in the PathwayBrowser

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Cell-Cell communication (Gallus gallus)

- Cell junction organization (Gallus gallus)
  - Cell-cell junction organization (Gallus gallus)
    - Adherens junctions interactions (Gallus gallus)
      - Activation of STAT3 by cadherin engagement (Gallus gallus)
        
        CDH1 forms homotypic trans-dimers (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Gallus gallus)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds F-actin (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds VCL (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Cell-to-cell contact through homophilic cadherin interactions inhibits RAC1/CDC42 ubiquitination (Gallus gallus)
        
        Engaged CDH1,(CDH11) [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Gallus gallus)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
      - Regulation of Homotypic Cell-Cell Adhesion (Gallus gallus)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Gallus gallus)
        
        Regulation of CDH1 Expression and Function (Gallus gallus)
        
        Regulation of CDH1 Function (Gallus gallus)
        
        CDH1 forms homotypic trans-dimers (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer cluster [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 trans-dimer [plasma membrane] (Gallus gallus)
        
        Man,Man9GlucNAc2,p-3S-CDH1:CTNNB1,JUP:CTNNA1:CTNND1:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        trans-homotypic CDH1 cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds F-actin (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        CDH1-associated CTNNA1 binds VCL (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin:VCL [plasma membrane] (Gallus gallus)
        
        Homotypic CDH1 cis-cluster:F-actin [plasma membrane] (Gallus gallus)
        
        F-actin (all) [cytosol] (Gallus gallus)
        
        actins:ATP [cytosol] (Gallus gallus)
        
        (ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)

Muscle contraction (Gallus gallus)

- Striated Muscle Contraction (Gallus gallus)
  - ATP Hydrolysis By Myosin (Gallus gallus)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
  - Calcium Binds Troponin-C (Gallus gallus)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
    - Inactive Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
  - Myosin Binds ATP (Gallus gallus)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
  - Release Of ADP From Myosin (Gallus gallus)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Gallus gallus)
        
        alpha Actin Chain [cytosol] (Gallus gallus)
        
        ACTA1 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0Y055

Reference Genes

ENSEMBL:ENSGALG00010010295.1

UCSC:A0A8V0Y055

Other Identifiers

GO:0000166

GO:0001725

GO:0005524

GO:0005737

GO:0005856

GO:0005865

GO:0005884

GO:0015629

GO:0016787

GO:0030240

GT_A_87_P054731

GT_A_87_P219663

Participates

as a repeated unit of

alpha Actin Chain [cytosol] (Gallus gallus)

as a member of

(ACTA1,ACTC1),(ACTB,ACTG1),(ACTA2,ACTG2) (Gallus gallus)

Inferred From

alpha Actin [cytosol] (Homo sapiens)

ACTA1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSGALG00010010295, ENSGALT00010024572, ENSGALP00010013941

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