Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
OPRL1 [plasma membrane]
Stable Identifier
R-GGA-374731
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
OPRL1, R4GF58
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Peptide ligand-binding receptors (Gallus gallus)
Nociceptin receptor binds to nociceptin (Gallus gallus)
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
OPRL1 [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:R4GF58
Gene Names
OPRL1
Reference Genes
BioGPS Gene:419251 OPRL1
ENSEMBL:ENSGALG00010023269.1
KEGG:gga:419251 OPRL1
Monarch:419251 OPRL1
NCBI Gene:419251 OPRL1
UCSC:R4GF58 OPRL1
Reference Transcript
RefSeq:NM_001318978.3 OPRL1
Other Identifiers
419251
GO:0001626
GO:0004930
GO:0004985
GO:0005886
GO:0007165
GO:0007186
GO:0007193
GO:0007200
GO:0007218
GO:0007270
GO:0016020
GO:0019233
GO:0019722
GO:0031410
GO:0038003
GO:0042923
GO:0043005
GO:0050877
GO:0097060
Gga.12774.1.S1_at
GgaAffx.26673.1.S1_at
Participates
as an input of
Nociceptin receptor binds to nociceptin (Gallus gallus)
as a component of
Nociceptin receptor:Nociceptin [plasma membrane] (Gallus gallus)
Inferred From
OPRL1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001305907.1
ENSEMBL
ENSGALP00010034489
,
ENSGALT00010056747
,
ENSGALG00010023269
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text